Devika S Manickam
Overview
Explore the profile of Devika S Manickam including associated specialties, affiliations and a list of published articles.
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37
Citations
635
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Recent Articles
1.
Jhaveri J, Khare P, Pinky P, Kamte Y, Chandwani M, Milosevic J, et al.
Eur J Pharm Biopharm
. 2024 Sep;
204:114500.
PMID: 39303949
Extracellular vesicles (EVs) are an emerging class of drug carriers and are primarily reported to be internalized into recipient cells via a combination of endocytic routes such as clathrin-mediated, caveolae-mediated...
2.
Dave K, Venna V, Rao K, Stolz D, Brady B, Quaicoe V, et al.
J Control Release
. 2024 Jul;
373:803-822.
PMID: 39084466
Ischemic stroke-induced mitochondrial dysfunction in the blood-brain barrier-forming brain endothelial cells (BECs) results in long-term neurological dysfunction post-stroke. We previously reported data from a pilot study where intravenous administration of...
3.
Khare P, Edgecomb S, Hamadani C, Conway J, Tanner E, Manickam D
Nanoscale Adv
. 2024 Mar;
6(7):1853-1873.
PMID: 38545295
Lipidoid nanoparticles (LNPs) have transformed the field of drug delivery and are clinically used for the delivery of nucleic acids to liver and muscle targets. Post-intravenous administration, LNPs are naturally...
4.
Dave K, Venna V, Rao K, Stolz D, Brady B, Quaicoe V, et al.
bioRxiv
. 2024 Jan;
PMID: 38293207
Ischemic stroke-induced mitochondrial dysfunction in the blood-brain barrier-forming brain endothelial cells ( ) results in long-term neurological dysfunction post-stroke. We previously data from a pilot study where administration of human...
5.
Beloqui A, Ling D, Manickam D
J Control Release
. 2023 Dec;
365:801.
PMID: 38043728
No abstract available.
6.
Dave K, Stolz D, Manickam D
Expert Opin Drug Deliv
. 2023 Nov;
20(12):1769-1788.
PMID: 37921194
Introduction: Ischemic stroke-induced mitochondrial dysfunction in brain endothelial cells () leads to breakdown of the blood-brain barrier () causing long-term neurological dysfunction. Restoration of mitochondrial function in injured BECs is...
7.
Khare P, Edgecomb S, Hamadani C, Tanner E, Manickam D
Adv Drug Deliv Rev
. 2023 May;
197:114861.
PMID: 37150326
Lipid nanoparticles (LNPs) have revolutionized the field of drug delivery through their applications in siRNA delivery to the liver (Onpattro) and their use in the Pfizer-BioNTech and Moderna COVID-19 mRNA...
8.
Dave K, Zhao W, Hoover C, DSouza A, Manickam D
AAPS PharmSciTech
. 2023 Feb;
24(2):63.
PMID: 36759375
No abstract available.
9.
Dave K, Stolz D, Venna V, Quaicoe V, Maniskas M, Reynolds M, et al.
J Control Release
. 2023 Jan;
354:368-393.
PMID: 36642252
Ischemic stroke causes brain endothelial cell (BEC) death and damages tight junction integrity of the blood-brain barrier (BBB). We harnessed the innate mitochondrial load of BEC-derived extracellular vesicles (EVs) and...
10.
Dave K, Dobbins D, Farinelli M, Sullivan A, Milosevic J, Stolz D, et al.
Cell Mol Bioeng
. 2022 Nov;
15(5):367-389.
PMID: 36444353
Introduction: Extracellular vesicles (EVs) are promising carriers for the delivery of biotherapeutic cargo such as RNA and proteins. We have previously demonstrated that the innate EV mitochondria in microvesicles (MVs),...