Derya Shimshek
Overview
Explore the profile of Derya Shimshek including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
116
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0
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Recent Articles
1.
Rother C, Uhlmann R, Muller S, Schelle J, Skodras A, Obermuller U, et al.
Nat Commun
. 2022 Nov;
13(1):7333.
PMID: 36443293
Brain Aβ deposition is a key early event in the pathogenesis of Alzheimer´s disease (AD), but the long presymptomatic phase and poor correlation between Aβ deposition and clinical symptoms remain...
2.
Blume T, Filser S, Sgobio C, Peters F, Neumann U, Shimshek D, et al.
Front Aging Neurosci
. 2022 Aug;
14:909586.
PMID: 35936777
All clinical BACE1-inhibitor trials for the treatment of Alzheimer's Disease (AD) have failed due to insufficient efficacy or side effects like worsening of cognitive symptoms. However, the scientific evidence to...
3.
Dietrich M, Hecker C, Martin E, Langui D, Gliem M, Stankoff B, et al.
Neurol Neuroimmunol Neuroinflamm
. 2022 Mar;
9(3).
PMID: 35354603
Background And Objectives: Siponimod is an oral, selective sphingosine-1-phosphate receptor-1/5 modulator approved for treatment of multiple sclerosis. Methods: Mouse MRI was used to investigate remyelination in the cuprizone model. We...
4.
Streubel-Gallasch L, Giusti V, Sandre M, Tessari I, Plotegher N, Giusto E, et al.
Mol Neurobiol
. 2021 Feb;
58(7):3119-3140.
PMID: 33629273
Parkinson's disease (PD) is a neurodegenerative, progressive disease without a cure. To prevent PD onset or at least limit neurodegeneration, a better understanding of the underlying cellular and molecular disease...
5.
Shutinoski B, Hakimi M, Harmsen I, Lunn M, Rocha J, Lengacher N, et al.
Sci Transl Med
. 2019 Sep;
11(511).
PMID: 31554740
Variants in the leucine-rich repeat kinase-2 () gene are associated with Parkinson's disease, leprosy, and Crohn's disease, three disorders with inflammation as an important component. Because of its high expression...