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Derick M Duell

Explore the profile of Derick M Duell including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 161
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Recent Articles
1.
Varco-Merth B, Chaunzwa M, Duell D, Marenco A, Goodwin W, Dannay R, et al.
PLoS Pathog . 2024 Aug; 20(8):e1012496. PMID: 39173097
Persistence of the rebound-competent viral reservoir (RCVR) within the CD4+ T cell compartment of people living with HIV remains a major barrier to HIV cure. Here, we determined the effects...
2.
Eichholz K, Fukazawa Y, Peterson C, Haeseleer F, Medina M, Hoffmeister S, et al.
J Clin Invest . 2024 Apr; 134(7). PMID: 38557496
Programmed cell death protein 1 (PD-1) is an immune checkpoint marker commonly expressed on memory T cells and enriched in latently HIV-infected CD4+ T cells. We engineered an anti-PD-1 chimeric...
3.
Okoye A, DeGottardi M, Fukazawa Y, Vaidya M, Abana C, Konfe A, et al.
J Immunol . 2019 Oct; 203(11):2928-2943. PMID: 31653683
Although IL-15 has been implicated in the pathogenic hyperimmune activation that drives progressive HIV and SIV infection, as well as in the generation of HIV/SIV target cells, it also supports...
4.
Okoye A, Hansen S, Vaidya M, Fukazawa Y, Park H, Duell D, et al.
Nat Med . 2018 Aug; 24(9):1430-1440. PMID: 30082858
Prophylactic vaccination of rhesus macaques with rhesus cytomegalovirus (RhCMV) vectors expressing simian immunodeficiency virus (SIV) antigens (RhCMV/SIV) elicits immune responses that stringently control highly pathogenic SIV infection, with subsequent apparent...
5.
DeGottardi M, Okoye A, Vaidya M, Talla A, Konfe A, Reyes M, et al.
J Immunol . 2016 Jul; 197(4):1183-98. PMID: 27430715
IL-15 has been implicated as a key regulator of T and NK cell homeostasis in multiple systems; however, its specific role in maintaining peripheral T and NK cell populations relative...
6.
Okoye A, Rohankhedkar M, Konfe A, Abana C, Reyes M, Clock J, et al.
J Immunol . 2015 Sep; 195(9):4292-305. PMID: 26416281
Aging is associated with gradual deterioration of adaptive immune function, a hallmark of which is the profound loss of naive T cells (TN) associated with decline in thymic output and...