Richard Lum
Overview
Explore the profile of Richard Lum including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
9
Citations
1237
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Okoye A, DeGottardi M, Fukazawa Y, Vaidya M, Abana C, Konfe A, et al.
J Immunol
. 2019 Oct;
203(11):2928-2943.
PMID: 31653683
Although IL-15 has been implicated in the pathogenic hyperimmune activation that drives progressive HIV and SIV infection, as well as in the generation of HIV/SIV target cells, it also supports...
2.
Okoye A, Hansen S, Vaidya M, Fukazawa Y, Park H, Duell D, et al.
Nat Med
. 2018 Aug;
24(9):1430-1440.
PMID: 30082858
Prophylactic vaccination of rhesus macaques with rhesus cytomegalovirus (RhCMV) vectors expressing simian immunodeficiency virus (SIV) antigens (RhCMV/SIV) elicits immune responses that stringently control highly pathogenic SIV infection, with subsequent apparent...
3.
Fukazawa Y, Lum R, Okoye A, Park H, Matsuda K, Bae J, et al.
Nat Med
. 2015 Jan;
21(2):132-9.
PMID: 25599132
Chronic-phase HIV and simian immunodeficiency virus (SIV) replication is reduced by as much as 10,000-fold in elite controllers (ECs) compared with typical progressors (TPs), but sufficient viral replication persists in...
4.
Fukazawa Y, Park H, Cameron M, Lefebvre F, Lum R, Coombes N, et al.
Nat Med
. 2012 Sep;
18(11):1673-81.
PMID: 22961108
Live attenuated simian immunodeficiency virus (SIV) vaccines (LAVs) remain the most efficacious of all vaccines in nonhuman primate models of HIV and AIDS, yet the basis of their robust protection...
5.
Okoye A, Rohankhedkar M, Abana C, Pattenn A, Reyes M, Pexton C, et al.
J Exp Med
. 2012 Mar;
209(4):641-51.
PMID: 22451717
The development of AIDS in chronic HIV/simian immunodeficiency virus (SIV) infection has been closely linked to progressive failure of CD4(+) memory T cell (T(M)) homeostasis. CD4(+) naive T cells (T(N))...
6.
Okoye A, Park H, Rohankhedkar M, Coyne-Johnson L, Lum R, Walker J, et al.
J Exp Med
. 2009 Jun;
206(7):1575-88.
PMID: 19546246
Depletion of CD8(+) lymphocytes during acute simian immunodeficiency virus (SIV) infection of rhesus macaques (RMs) results in irreversible prolongation of peak-level viral replication and rapid disease progression, consistent with a...
7.
Okoye A, Meier-Schellersheim M, Brenchley J, Hagen S, Walker J, Rohankhedkar M, et al.
J Exp Med
. 2007 Aug;
204(9):2171-85.
PMID: 17724130
Primary simian immunodeficiency virus (SIV) infections of rhesus macaques result in the dramatic depletion of CD4(+) CCR5(+) effector-memory T (T(EM)) cells from extra-lymphoid effector sites, but in most infections, an...
8.
Picker L, Hagen S, Lum R, Reed-Inderbitzin E, Daly L, Sylwester A, et al.
J Exp Med
. 2004 Nov;
200(10):1299-314.
PMID: 15545355
The mechanisms linking human immunodeficiency virus replication to the progressive immunodeficiency of acquired immune deficiency syndrome are controversial, particularly the relative contribution of CD4+ T cell destruction. Here, we used...
9.
Pitcher C, Hagen S, Walker J, Lum R, Mitchell B, Maino V, et al.
J Immunol
. 2001 Dec;
168(1):29-43.
PMID: 11751943
The rhesus macaque (RM) is a critical animal model for studies of viral pathogenesis and immunity, yet fundamental aspects of their cellular immune response remain poorly defined. One such deficiency...