Derek N J Hart
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Explore the profile of Derek N J Hart including associated specialties, affiliations and a list of published articles.
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64
Citations
1955
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Recent Articles
21.
Christensen M, Turner B, Sinfield L, Kollar K, Cullup H, Waterhouse N, et al.
Haematologica
. 2010 Aug;
95(12):2102-10.
PMID: 20801899
Background: Multipotent mesenchymal stromal cells suppress T-cell function in vitro, a property that has underpinned their use in treating clinical steroid-refractory graft-versus-host disease after allogeneic hematopoietic stem cell transplantation. However...
22.
Jongbloed S, Kassianos A, McDonald K, Clark G, Ju X, Angel C, et al.
J Exp Med
. 2010 May;
207(6):1247-60.
PMID: 20479116
The characterization of human dendritic cell (DC) subsets is essential for the design of new vaccines. We report the first detailed functional analysis of the human CD141+ DC subset. CD141+...
23.
Kassianos A, Jongbloed S, Hart D, Radford K
Methods Mol Biol
. 2009 Nov;
595:45-54.
PMID: 19941104
Human blood dendritic cells (DCs) are a rare, heterogeneous cell population that comprise approximately 1% of circulating peripheral blood mononuclear cells (PBMCs). Their isolation has been confounded by their scarcity...
24.
Ju X, Clark G, Hart D
Methods Mol Biol
. 2009 Nov;
595:3-20.
PMID: 19941102
Dendritic cells (DC) are critical to the induction and regulation of the innate and adaptive immune responses. They have been implicated in the pathogenesis of many autoimmune and chronic inflammatory...
25.
Clark G, Ju X, Azlan M, Tate C, Ding Y, Hart D
Immunobiology
. 2009 Jul;
214(9-10):730-6.
PMID: 19592130
The CD300 glycoproteins are a family of related leucocyte surface molecules that modulate a diverse array of cell processes via their paired triggering and inhibitory receptor functions. All family members...
26.
Hardy M, Kassianos A, Vulink A, Wilkinson R, Jongbloed S, Hart D, et al.
Immunol Cell Biol
. 2009 Jun;
87(8):606-14.
PMID: 19546878
Dendritic cells differentiated from monocytes (MoDC) in the presence of GM-CSF and IL-15 (IL-15 MoDC) exhibit superior migration and cytotoxic T-lymphocyte (CTL) induction compared with MoDC differentiated in IL-4 and...
27.
Clark G, Ju X, Tate C, Hart D
Trends Immunol
. 2009 Apr;
30(5):209-17.
PMID: 19359216
The CD300 glycoproteins are a family of cell surface molecules that modulate a diverse array of cell processes via their paired triggering and inhibitory receptor functions. Family members share a...
28.
Wilson J, Cullup H, Lourie R, Sheng Y, Palkova A, Radford K, et al.
J Exp Med
. 2009 Jan;
206(2):387-98.
PMID: 19171763
Allogeneic (allo) hematopoietic stem cell transplantation is an effective therapy for hematological malignancies but it is limited by acute graft-versus-host disease (GVHD). Dendritic cells (DC) play a major role in...
29.
Turner B, Kambouris M, Sinfield L, Lange J, Burns A, Lourie R, et al.
Transplantation
. 2008 Oct;
86(7):968-76.
PMID: 18852664
Background: Preparative myeloablative conditioning regimens for allogeneic hematopoietic stem-cell transplantation (HSCT) may control malignancy and facilitate engraftment but also contribute to transplant related mortality, cytokine release, and acute graft-versus-host disease...
30.
Liu X, Hart D, Macpherson G, Good M, Wykes M
Immunology
. 2008 Sep;
125(1):14-20.
PMID: 18798916
The development and maintenance of memory B cells (MBC) is dependent on germinal centres (GC) with follicular dendritic cell (FDC) networks. We have previously shown that FDC networks within GC...