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Derek Miller

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Articles 76
Citations 1812
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Recent Articles
1.
Garcia-Flores V, Liu Z, Romero R, Pique-Regi R, Xu Y, Miller D, et al.
J Immunol . 2024 Oct; 213(11):1620-1634. PMID: 39431882
Preterm birth (PTB), often preceded by preterm labor, is a major cause of neonatal morbidity and mortality worldwide. Most PTB cases involve intra-amniotic inflammation without detectable microorganisms, termed in utero...
2.
Somani S, Takhar S, Miller D, Camarillo H, Zhu M, Tran K
Explor Res Clin Soc Pharm . 2024 Jul; 15:100462. PMID: 38983636
Background: Compass Rose™, a case management tool developed by Epic®, was designed to track various patient coordination tasks, outreaches, and outcomes. This report describes the implementation of Compass Rose™ within...
3.
Xu Y, Miller D, Galaz J, Gomez-Lopez N
Methods Mol Biol . 2024 Mar; 2781:155-162. PMID: 38502451
Immunophenotyping allows for the deep characterization of leukocytes present in biological samples. Here, we describe a complete procedure for the immunophenotyping of amniotic fluid, which can provide information into the...
4.
Garcia-Flores V, Miller D, Galaz J, Gomez-Lopez N
Methods Mol Biol . 2024 Mar; 2781:143-154. PMID: 38502450
The dissociation of whole tissue into single-cell suspensions is a critical step for techniques focused on profiling of individual cells. Here, we describe a protocol for the preparation of high-quality...
5.
Garcia-Flores V, Romero R, Tarca A, Peyvandipour A, Xu Y, Galaz J, et al.
Sci Transl Med . 2024 Jan; 16(729):eadh8335. PMID: 38198568
Labor is a complex physiological process requiring a well-orchestrated dialogue between the mother and fetus. However, the cellular contributions and communications that facilitate maternal-fetal cross-talk in labor have not been...
6.
Galaz J, Romero R, Greenberg J, Theis K, Arenas-Hernandez M, Xu Y, et al.
iScience . 2023 Dec; 26(12):108341. PMID: 38047079
Preterm birth, the leading cause of perinatal morbidity, often follows premature labor, a syndrome whose prevention remains a challenge. To better understand the relationship between premature labor and host-microbiome interactions,...
7.
Farias-Jofre M, Romero R, Galaz J, Xu Y, Miller D, Garcia-Flores V, et al.
EBioMedicine . 2023 Nov; 98:104865. PMID: 37944273
Background: Preterm birth preceded by spontaneous preterm labour often occurs in the clinical setting of sterile intra-amniotic inflammation (SIAI), a condition that currently lacks treatment. Methods: Proteomic and scRNA-seq human...
8.
Miller D, Romero R, Myers L, Xu Y, Arenas-Hernandez M, Galaz J, et al.
J Immunol . 2023 Aug; 211(7):1082-1098. PMID: 37647360
T cells are implicated in the pathophysiology of preterm labor and birth, the leading cause of neonatal morbidity and mortality worldwide. Specifically, maternal decidual T cells infiltrate the chorioamniotic membranes...
9.
Kanninen T, Tao L, Romero R, Xu Y, Arenas-Hernandez M, Galaz J, et al.
Hum Immunol . 2023 Jul; 84(9):450-463. PMID: 37422429
The aim of this study was to establish the role of thymic stromal lymphopoietin (TSLP) in the intra-amniotic host response of women with spontaneous preterm labor (sPTL) and birth. Amniotic...
10.
Farias-Jofre M, Romero R, Xu Y, Levenson D, Tao L, Kanninen T, et al.
BMC Pregnancy Childbirth . 2023 May; 23(1):323. PMID: 37149573
Background: Viral infections during pregnancy can have deleterious effects on mothers and their offspring. Monocytes participate in the maternal host defense against invading viruses; however, whether pregnancy alters monocyte responses...