Dennis E Kyle
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Explore the profile of Dennis E Kyle including associated specialties, affiliations and a list of published articles.
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138
Citations
3279
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Recent Articles
1.
Russell A, Dainis J, Alexander J, Ali I, Kyle D
bioRxiv
. 2025 Jan;
PMID: 39868105
Rapid and accurate diagnostics are needed to effectively detect and treat primary amoebic meningoencephalitis (PAM) caused by (). Delayed diagnosis and similarities to other causes of meningitis contribute to a...
2.
Nguyen G, Cooper C, McWhorter O, Sharma R, Elliot A, Ruberto A, et al.
Malar J
. 2024 Nov;
23(1):357.
PMID: 39580415
Background: Malaria, a disease caused by parasites of the genus Plasmodium, continues to impact many regions globally. The rise in resistance to artemisinin-based anti-malarial drugs highlights the need for new...
3.
Marques-da-Silva C, Schmidt-Silva C, Bowers C, Charles-Chess E, Shiau J, Park E, et al.
bioRxiv
. 2024 Nov;
PMID: 39484443
parasites undergo development and replication within the hepatocytes before infecting the erythrocytes and initiating clinical malaria. Although type-I interferons (IFNs) are known to hinder infection within the liver, the underlying...
4.
Van Horn K, Zhao Y, Parvatkar P, Maier J, Mutka T, Lacrue A, et al.
Eur J Med Chem
. 2024 Jun;
275:116599.
PMID: 38909569
The increase in research funding for the development of antimalarials since 2000 has led to a surge of new chemotypes with potent antimalarial activity. High-throughput screens have delivered several thousand...
5.
Shiau J, Garcia-Diaz N, Kyle D, Pathak A
Parasit Vectors
. 2024 May;
17(1):236.
PMID: 38783366
Background: Like other oviparous organisms, the gonotrophic cycle of mosquitoes is not complete until they have selected a suitable habitat to oviposit. In addition to the evolutionary constraints associated with...
6.
Christensen P, Cinzah R, Suwanarusk R, Chua A, Kaneko O, Kyle D, et al.
Antimicrob Agents Chemother
. 2024 Apr;
68(5):e0028024.
PMID: 38587391
Testing antimicrobial sensitivity is limited to schizont maturation assays, which preclude determining the IC50s of delayed action antimalarials such as doxycycline. Using as a model for , we determined the...
7.
Parvatkar P, Maher S, Zhao Y, Cooper C, de Castro S, Peneau J, et al.
J Nat Prod
. 2024 Jan;
87(2):315-321.
PMID: 38262446
Trichothecenes (TCNs) are a large group of tricyclic sesquiterpenoid mycotoxins that have intriguing structural features and remarkable biological activities. Herein, we focused on three TCNs (anguidine, verrucarin A, and verrucarol)...
8.
Pathak A, Shiau J, Freitas R, Kyle D
One Health
. 2023 Nov;
17:100582.
PMID: 38024285
Ingestion of an additional blood meal(s) by a hematophagic insect can accelerate development of several vector-borne parasites and pathogens. Most studies, however, offer blood from the same vertebrate host species...
9.
Ferrins L, Buskes M, Kapteyn M, Engels H, Enos S, Lu C, et al.
Front Microbiol
. 2023 Nov;
14:1304196.
PMID: 37954236
[This corrects the article DOI: 10.3389/fmicb.2023.1149145.].
10.
Kassu M, Parvatkar P, Milanes J, Monaghan N, Kim C, Dowgiallo M, et al.
ACS Infect Dis
. 2023 Oct;
9(11):2190-2201.
PMID: 37820055
Pathogenic free-living amoebae (pFLA) can cause life-threatening central nervous system (CNS) infections and warrant the investigation of new chemical agents to combat the rise of infection from these pathogens. glucokinase...