Denise Monack
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Explore the profile of Denise Monack including associated specialties, affiliations and a list of published articles.
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18
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1144
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Recent Articles
1.
Monack D, Butler D, Luccia B, Vilches-Moure J
Res Sq
. 2025 Jan;
PMID: 39801515
can persist asymptomatically within tissues for extended periods. This remarkable feat is achieved through intricate host-pathogen interactions in immune cell aggregates called granulomas, wherein find favorable cellular niches to exploit...
2.
Haileselassie B, Mukherjee R, Joshi A, Napier B, Massis L, Ostberg N, et al.
J Mol Cell Cardiol
. 2023 Nov;
187:120.
PMID: 38000978
No abstract available.
3.
Mukherjee R, Tompkins C, Ostberg N, Joshi A, Massis L, Vijayan V, et al.
Crit Care Med
. 2022 Jan;
50(6):e504-e515.
PMID: 35067534
Objectives: Recent publications have shown that mitochondrial dynamics can govern the quality and quantity of extracellular mitochondria subsequently impacting immune phenotypes. This study aims to determine if pathologic mitochondrial fission...
4.
Haileselassie B, Mukherjee R, Joshi A, Napier B, Massis L, Ostberg N, et al.
J Mol Cell Cardiol
. 2019 Apr;
130:160-169.
PMID: 30981733
Methods: H9C2 cardiomyocytes were treated with lipopolysaccharide (LPS) to evaluate changes in mitochondrial membrane potential, oxidative stress, cellular respiration, and mitochondrial morphology. Balb/c mice were treated with LPS, cardiac function...
5.
Jacobson A, Lam L, Rajendram M, Tamburini F, Honeycutt J, Pham T, et al.
Cell Host Microbe
. 2018 Jul;
24(2):296-307.e7.
PMID: 30057174
The intestinal microbiota provides colonization resistance against pathogens, limiting pathogen expansion and transmission. These microbiota-mediated mechanisms were previously identified by observing loss of colonization resistance after antibiotic treatment or dietary...
6.
Carden S, Walker G, Honeycutt J, Lugo K, Pham T, Jacobson A, et al.
Cell Host Microbe
. 2017 Feb;
21(2):182-194.
PMID: 28182950
Genome degradation correlates with host adaptation and systemic disease in Salmonella. Most lineages of the S. enterica subspecies Typhimurium cause gastroenteritis in humans; however, the recently emerged ST313 lineage II...
7.
Hotson A, Gopinath S, Nicolau M, Khasanova A, Finck R, Monack D, et al.
Sci Signal
. 2016 Jan;
9(410):ra4.
PMID: 26758212
The immune system enacts a coordinated response when faced with complex environmental and pathogenic perturbations. We used the heterogeneous responses of mice to persistent Salmonella infection to model system-wide coordination...
8.
Carden S, Okoro C, Dougan G, Monack D
Pathog Dis
. 2015 Mar;
73(4).
PMID: 25808600
Salmonella is an enteric pathogen that causes a range of diseases in humans. Non-typhoidal Salmonella (NTS) serovars such as Salmonella enterica serovar Typhimurium generally cause a self-limiting gastroenteritis whereas typhoidal...
9.
Gopinath S, Hotson A, Johns J, Nolan G, Monack D
PLoS Pathog
. 2013 Jun;
9(6):e1003408.
PMID: 23754944
Host-to-host transmission of a pathogen ensures its successful propagation and maintenance within a host population. A striking feature of disease transmission is the heterogeneity in host infectiousness. It has been...
10.
Qu Y, Misaghi S, Izrael-Tomasevic A, Newton K, Gilmour L, Lamkanfi M, et al.
Nature
. 2012 Aug;
490(7421):539-42.
PMID: 22885697
NLRC4 is a cytosolic member of the NOD-like receptor family that is expressed in innate immune cells. It senses indirectly bacterial flagellin and type III secretion systems, and responds by...