Denise M OSullivan
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Explore the profile of Denise M OSullivan including associated specialties, affiliations and a list of published articles.
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34
Citations
768
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Recent Articles
1.
Falak S, OSullivan D, Cleveland M, Cowen S, Busby E, Devonshire A, et al.
Clin Chem
. 2024 Dec;
71(3):378-386.
PMID: 39724302
Background: Nucleic acid amplification tests (NAATs) assist in the diagnosis of numerous infectious diseases. They are typically sensitive and specific and can be quickly developed and adapted. Far more challenging...
2.
Huggett J, OSullivan D, Cowen S, Cleveland M, Davies K, Harris K, et al.
Mol Aspects Med
. 2024 May;
97:101275.
PMID: 38772082
Diagnostic tests were heralded as crucial during the Coronavirus disease (COVID-19) pandemic with most of the key methods using bioanalytical approaches that detected larger molecules (RNA, protein antigens or antibodies)...
3.
Gartner K, Dominguez-Rodriguez S, Heaney J, Gkouleli T, Grant P, Dorgham K, et al.
Front Immunol
. 2024 Mar;
15:1334236.
PMID: 38444847
Introduction: Initiation of antiretroviral treatment (ART) in patients early after HIV-infection and long-term suppression leads to low or undetectable levels of HIV RNA and cell-associated (CA) HIV DNA and RNA....
4.
Vierbaum L, Wojtalewicz N, Grunert H, Zimmermann A, Scholz A, Goseberg S, et al.
Sci Rep
. 2023 Aug;
13(1):13206.
PMID: 37580353
The COVID-19 pandemic illustrated the important role of diagnostic tests, including lateral flow tests (LFTs), in identifying patients and their contacts to slow the spread of infections. INSTAND performed external...
5.
Busby E, Doyle R, Leboreiro Babe C, Harris K, Mack D, Mendez-Cervantes G, et al.
Microbiol Spectr
. 2023 May;
11(3):e0499522.
PMID: 37154773
Colonization and subsequent health care-associated infection (HCAI) with Acinetobacter baumannii are a concern for vulnerable patient groups within the hospital setting. Outbreaks involving multidrug-resistant strains are associated with increased patient...
6.
Mercer T, Almond N, Crone M, Chain P, Deshpande A, Eveleigh D, et al.
Nat Biotechnol
. 2022 Nov;
40(11):1563-1568.
PMID: 36323792
No abstract available.
7.
Huggett J, French D, OSullivan D, Moran-Gilad J, Zumla A
Euro Surveill
. 2022 Aug;
27(32).
PMID: 35959687
Monkeypox was declared a public health emergency of international concern by the World Health Organization (WHO) on 23 July 2022. Between 1 January and 23 July 2022, 16,016 laboratory confirmed...
8.
Le Duff Y, Gartner K, Busby E, Dalzini A, Danaviah S, Jimenez Fuentes J, et al.
Microbiol Spectr
. 2022 Jun;
10(3):e0024322.
PMID: 35658711
Reliable and accurate quantification of cell-associated HIV DNA (CA HIV DNA) is critical for early infant diagnosis, clinical management of patients under therapy, and to inform new therapeutics efficacy. The...
9.
Storey N, Brown J, Pereira R, OSullivan D, Huggett J, Williams R, et al.
J Clin Virol Plus
. 2022 Mar;
1(3):100037.
PMID: 35262020
Reverse transcriptase quantitative PCR (RT-qPCR) is the main diagnostic assay used to detect SARS-CoV-2 RNA in respiratory samples. RT-qPCR is performed by specifically targeting the viral genome using complementary oligonucleotides...
10.
Evans D, Cowen S, Kammel M, OSullivan D, Stewart G, Grunert H, et al.
Clin Chem
. 2021 Oct;
68(1):153-162.
PMID: 34633030
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA quantities, measured by reverse transcription quantitative PCR (RT-qPCR), have been proposed to stratify clinical risk or determine analytical performance targets. We...