Defu Zeng
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Explore the profile of Defu Zeng including associated specialties, affiliations and a list of published articles.
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62
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1883
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Recent Articles
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Li Q, Wang X, Song Q, Yang S, Wu X, Yang D, et al.
J Clin Invest
. 2023 Aug;
133(15).
PMID: 37526084
STAT3 deficiency (STAT3-/-) in donor T cells prevents graft-versus-host disease (GVHD), but the impact on graft-versus-leukemia (GVL) activity and mechanisms of GVHD prevention remains unclear. Here, using murine models of...
3.
Tompkins J, Lizhar E, Shokrani A, Wu X, Berley J, Kamali D, et al.
Cell Rep Methods
. 2023 Jun;
3(5):100465.
PMID: 37323577
Cellular differentiation requires global changes to DNA methylation (DNAme), where it functions to regulate transcription factor, chromatin remodeling activity, and genome interpretation. Here, we describe a simple DNAme engineering approach...
4.
Huang Y, Wu X, Tang S, Wu H, Nasri U, Qin Q, et al.
Am J Transplant
. 2023 Apr;
23(8):1116-1129.
PMID: 37105316
Induction of major histocompatibility complex (MHC) human leukocyte antigen (HLA)-mismatched mixed chimerism is a promising approach for organ transplantation tolerance; however, human leukocyte antigen-mismatched stable mixed chimerism has not been...
5.
Zhang Y, Song Q, Cassady K, Lee M, Tang H, Zheng M, et al.
Proc Natl Acad Sci U S A
. 2023 Apr;
120(16):e2205085120.
PMID: 37036990
PD-L1 has two receptors: PD-1 and CD80. Previous reports assumed that PD-L1 and CD80 interacted in trans, but recent reports showed that only cis PD-L1/CD80 interactions existed, and prevention of...
6.
Buxbaum N, Socie G, Hill G, MacDonald K, Tkachev V, Teshima T, et al.
Blood Adv
. 2022 Nov;
7(17):4886-4902.
PMID: 36322878
Chronic graft-versus-host disease (cGvHD) remains a prominent barrier to allogeneic hematopoietic stem cell transplantion as the leading cause of nonrelapse mortality and significant morbidity. Tremendous progress has been achieved in...
7.
Zeng D, Li Y, Xia T, Cui F, Zhang J
ACS Omega
. 2022 Sep;
7(37):33482-33490.
PMID: 36157751
Designing economical and nonprecious catalysts with a catalytic performance as good as that of noble metals is of great importance in future renewable bioenergy production. In this study, the metal-organic...
8.
Zhao X, Yang W, Yu T, Yu Y, Cui X, Zhou Z, et al.
Gastroenterology
. 2022 Sep;
164(1):89-102.
PMID: 36113570
Background & Aims: Intestinal fibrosis is a significant complication of Crohn's disease (CD). Gut microbiota reactive Th17 cells are crucial in the pathogenesis of CD; however, how Th17 cells induce...
9.
Kong X, Wu X, Wang B, Zeng D, Cassady K, Nasri U, et al.
Blood
. 2022 Sep;
140(25):2740-2753.
PMID: 36084473
Chronic graft-versus-host disease (cGVHD) is an autoimmune-like syndrome. CXCR5-PD-1hi peripheral T-helper (Tph) cells have an important pathogenic role in autoimmune diseases, but the role of Tph cells in cGVHD remains...
10.
Xiong Z, Zeng D, Shen S, Han Z
Comput Math Methods Med
. 2022 Aug;
2022:4525892.
PMID: 36017154
Background: Intracranial infection is a serious complication after neurosurgery. According to a survey, the incidence of intracranial infection is about 2.2%-2.6%, and patients with severe symptoms may even pose a...