Fouad Kandeel
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Explore the profile of Fouad Kandeel including associated specialties, affiliations and a list of published articles.
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Articles
132
Citations
3621
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Recent Articles
1.
Rickels M, Ballou C, Foster N, Alejandro R, Baidal D, Bellin M, et al.
Diabetes Care
. 2025 Feb;
PMID: 39951130
Objective: Islet transplantation was recently US Food and Drug Administration approved for adults with type 1 diabetes complicated by recurrent severe hypoglycemia events (SHEs). We sought to understand the long-term...
2.
Wang C, Orr C, Hacker-Stratton J, El-Shahawy M, Omori K, Qi M, et al.
Cell Transplant
. 2025 Jan;
34:9636897241310989.
PMID: 39881535
Although islet transplantation is effective in reducing severe hypoglycemia events and controlling blood glucose in patients with type 1 diabetes, maintaining islet graft function long-term is a significant challenge. Islets...
3.
Isenberg J, Kandeel F
Cell Transplant
. 2025 Jan;
34():9636897241312801.
PMID: 39831598
Islet transplantation (IT) is a successful natural cell therapy. But the benefits are known mostly to individuals with severe type 1 diabetes who undergo IT and the health care professionals...
4.
Orr C, Stratton J, El-Shahawy M, Forouhar E, Peng A, Singh G, et al.
Cell Transplant
. 2025 Jan;
34():9636897241309412.
PMID: 39780302
Herein, we characterized the percentage of tacrolimus to the combined sirolimus and tacrolimus trough levels (tacrolimus %) observed during islet transplant-associated immune suppression therapy with post-transplant skin cancer. Although trough...
5.
Esparza D, Lima C, Abuelreich S, Ghaeli I, Hwang J, Oh E, et al.
Front Endocrinol (Lausanne)
. 2024 Nov;
15:1451279.
PMID: 39497805
Introduction: Double C2-like domain beta (DOC2B) is a vesicle priming protein critical for glucose-stimulated insulin secretion in β-cells. Individuals with type 1 diabetes (T1D) have lower levels of DOC2B in...
6.
Lenz G, Miao L, Lenz A, Mares J, Quijano J, Zook H, et al.
Pancreas
. 2024 Sep;
53(10):e818-e829.
PMID: 39259841
Objective: Islet transplantation is an effective treatment for type 1 diabetes. However, transplant success depends on quick islet assessment because islets deteriorate 2-3 days after isolation. A new tool, single-cell...
7.
Kato M, Abdollahi M, Omori K, Malek V, Lanting L, Kandeel F, et al.
Mol Ther Nucleic Acids
. 2024 Jul;
35(3):102252.
PMID: 39071954
We investigated the role of the endoplasmic reticulum (ER) stress-regulated long noncoding RNA (lncRNA) lncMGC in pancreatic islets and the pathology of type 1 diabetes (T1D), as well as the...
8.
Ortiz J, Ghazalli N, Lopez K, Rawson J, McCown E, Oh E, et al.
Diabetes
. 2024 Jun;
73(9):1447-1461.
PMID: 38905124
Article Highlights:
9.
Kato H, Salgado M, Mendez D, Gonzalez N, Rawson J, Ligot D, et al.
Sci Rep
. 2024 May;
14(1):12402.
PMID: 38811610
Evaluating the quality of isolated human islets before transplantation is crucial for predicting the success in treating Type 1 diabetes. The current gold standard involves time-intensive in vivo transplantation into...
10.
Cobb J, Rawson J, Gonzalez N, Orr C, Kandeel F, Husseiny M
PLoS One
. 2024 May;
19(5):e0303863.
PMID: 38781241
Type 1 diabetes (T1D)-associated hyperglycemia develops, in part, from loss of insulin-secreting beta cells. The degree of glycemic dysregulation and the age at onset of disease can serve as indicators...