Deepti R Nagarkar
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Explore the profile of Deepti R Nagarkar including associated specialties, affiliations and a list of published articles.
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18
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1167
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Recent Articles
1.
Younginger B, Mayba O, Reeder J, Nagarkar D, Modrusan Z, Albert M, et al.
Cell Rep Med
. 2023 Jan;
4(2):100920.
PMID: 36706753
While the association between colorectal cancer (CRC) features and Fusobacterium has been extensively studied, less is known of other intratumoral bacteria. Here, we leverage whole transcriptomes from 807 CRC samples...
2.
Byrd A, Liu M, Fujimura K, Lyalina S, Nagarkar D, Charbit B, et al.
J Exp Med
. 2020 Nov;
218(1).
PMID: 33175106
As microbial therapeutics are increasingly being tested in diverse patient populations, it is essential to understand the host and environmental factors influencing the microbiome. Through analysis of 1,359 gut microbiome...
3.
Shikotra A, Choy D, Siddiqui S, Arthur G, Nagarkar D, Jia G, et al.
J Immunol
. 2017 Mar;
198(8):3307-3317.
PMID: 28275137
Severe asthma represents a major unmet clinical need; understanding the pathophysiology is essential for the development of new therapies. Using microarray analysis, we previously found three immunological clusters in asthma:...
4.
Choy D, Hart K, Borthwick L, Shikotra A, Nagarkar D, Siddiqui S, et al.
Sci Transl Med
. 2015 Aug;
7(301):301ra129.
PMID: 26290411
Increasing evidence suggests that asthma is a heterogeneous disorder regulated by distinct molecular mechanisms. In a cross-sectional study of asthmatics of varying severity (n = 51), endobronchial tissue gene expression...
5.
Nagarkar D, Ramirez-Carrozzi V, Choy D, Lee K, Soriano R, Jia G, et al.
J Allergy Clin Immunol
. 2015 Mar;
136(1):202-5.
PMID: 25784274
No abstract available.
6.
Nagarkar D, Poposki J, Tan B, Comeau M, Peters A, Hulse K, et al.
J Allergy Clin Immunol
. 2013 May;
132(3):593-600.e12.
PMID: 23688414
Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) is associated with TH2-dominant inflammation. Thymic stromal lymphopoietin (TSLP) is a cytokine that triggers dendritic cell-mediated TH2 inflammatory responses and that enhances IL-1-dependent...
7.
Schneider D, Hong J, Bowman E, Chung Y, Nagarkar D, McHenry C, et al.
Am J Physiol Lung Cell Mol Physiol
. 2012 Dec;
304(3):L162-9.
PMID: 23204071
Human rhinovirus (HRV) infections lead to exacerbations of lower airways disease in asthmatic patients but not in healthy individuals. However, underlying mechanisms remain to be completely elucidated. We hypothesized that...
8.
Nagarkar D, Poposki J, Comeau M, Biyasheva A, Avila P, Schleimer R, et al.
J Allergy Clin Immunol
. 2012 May;
130(1):225-32.e4.
PMID: 22633328
Background: Airway epithelial cells are important regulators of innate and adaptive immunity. Although mast cells are known to play a central role in manifestations of allergic inflammation and are found...
9.
Peterson S, Poposki J, Nagarkar D, Chustz R, Peters A, Suh L, et al.
J Allergy Clin Immunol
. 2011 Sep;
129(1):119-27.e1-9.
PMID: 21943944
Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) is associated with T(H)2-dominant inflammation, including eosinophilia, which is in contrast to chronic rhinosinusitis (CRS) without nasal polyps (NPs). CC chemokine ligand 18...
10.
Wang Q, Miller D, Bowman E, Nagarkar D, Schneider D, Zhao Y, et al.
PLoS Pathog
. 2011 Jun;
7(5):e1002070.
PMID: 21637773
Rhinovirus (RV), a single-stranded RNA picornavirus, is the most frequent cause of asthma exacerbations. We previously demonstrated in human bronchial epithelial cells that melanoma differentiation-associated gene (MDA)-5 and the adaptor...