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Debabrata Mahapatra

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Articles 18
Citations 55
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Recent Articles
1.
Mahapatra D, Maronpot R
Toxicol Pathol . 2024 Mar; 51(7-8):482-486. PMID: 38494947
Animals models are essential to understand the complex pathobiology of human diseases. George Box's aphorism based on statistics "All models are wrong, but some are useful" certainly applies to animal...
2.
Trempus C, Papas B, Sifre M, Bortner C, Scappini E, Tucker C, et al.
JCI Insight . 2023 Oct; 8(22). PMID: 37824216
Aberrant fibroblast function plays a key role in the pathogenesis of idiopathic pulmonary fibrosis, a devastating disease of unrelenting extracellular matrix deposition in response to lung injury. Platelet-derived growth factor...
3.
Foster M, Mahapatra D, Maronpot R, Nishino M, Chiba S, Koyanagi M, et al.
Regul Toxicol Pharmacol . 2023 Aug; 144:105472. PMID: 37611796
Gardenia blue powder was administered at 0.5%, 2.5%, or 5.0% in feed to male and female Sprague Dawley rats in an Extended One-Generation Reproductive Toxicity Study (OECD Test Guideline 443)....
4.
Fessler M, Madenspacher J, Baker P, Hilligan K, Bohrer A, Castro E, et al.
Am J Respir Cell Mol Biol . 2023 Aug; 69(6):638-648. PMID: 37578898
Oxysterols (i.e., oxidized cholesterol species) have complex roles in biology. 25-Hydroxycholesterol (25HC), a product of the activity of cholesterol-25-hydroxylase (CH25H) on cholesterol, has recently been shown to be broadly antiviral,...
5.
Maronpot R, Streicker M, Mahapatra D, Moore R, Koyanagi M, Chiba S, et al.
J Toxicol Pathol . 2023 Aug; 36(3):171-179. PMID: 37577364
Toxicity assessment of the food colorant Ellis at dietary exposures of 0.0%, 0.1%, 0.5%, 1.5%, 3.0% and 5.0% included measures of T-cell- dependent antibody response, neurotoxicity, and clinical and anatomic...
6.
Letsinger A, Ward J, Fannin R, Mahapatra D, Bridge M, Sills R, et al.
Sci Rep . 2023 Feb; 13(1):2042. PMID: 36739463
Individuals infected by SARS-CoV-2 are at risk of developing neurological-related post-acute disorders. Disputed epidemiological data indicated nicotine may reduce the severity of infection. Here we find exposure to nicotine in...
7.
Letsinger A, Ward J, Fannin R, Mahapatra D, Bridge M, Sills R, et al.
Res Sq . 2022 Nov; PMID: 36380754
Individuals infected by SARS-CoV-2 are at risk of developing neurological-related post-acute disorders. Disputed epidemiological data indicated nicotine may reduce the severity of infection. Here we find exposure to nicotine in...
8.
Hamm J, Mahapatra D, Knuth M, Abedini J, Lingerfelt M, Ekins S, et al.
Curr Res Toxicol . 2022 Nov; 3:100092. PMID: 36353521
Toxicology in the 21st Century (Tox21) is a federal collaboration employing a high-throughput robotic screening system to test 10,000 environmental chemicals. One of the primary goals of the program is...
9.
Fessler M, Madenspacher J, Baker P, Hilligan K, Castro E, Meacham J, et al.
bioRxiv . 2022 Oct; PMID: 36263064
Oxysterols (i.e., oxidized cholesterol species) have complex roles in biology. 25-hydroxycholesterol (25HC), a product of activity of cholesterol-25-hydroxylase (CH25H) upon cholesterol, has recently been shown to be broadly antiviral, suggesting...
10.
Mahapatra D, Donahue D, Nyska A, Hayashi S, Koyanagi M, Maronpot R
Food Chem Toxicol . 2021 Mar; 151:112103. PMID: 33771599
alpha-Glycosyl Isoquercitrin (AGIQ), is used in Japan as a food additive and was granted generally recognized as safe (GRAS) status in 2005 (FEMA) and 2007 (FDA). The safety and toxicity...