» Authors » Dayton J Goodell

Dayton J Goodell

Explore the profile of Dayton J Goodell including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 13
Citations 219
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
Goodell D, Whitby F, Mellem J, Lei N, Brockie P, Maricq A, et al.
Cell Rep . 2024 Jan; 43(2):113694. PMID: 38265937
N-methyl-D-aspartate (NMDA)-type ionotropic glutamate receptors have essential roles in neurotransmission and synaptic plasticity. Previously, we identified an evolutionarily conserved protein, NRAP-1, that is required for NMDA receptor (NMDAR) function in...
2.
Goodell D, Tullis J, Bayer K
J Neurophysiol . 2021 Apr; 125(5):1973-1981. PMID: 33881939
The death-associated protein kinase 1 (DAPK1) has recently been shown to have a physiological function in long-term depression (LTD) of glutamatergic synapses: acute inhibition of DAPK1 blocked the LTD that...
3.
Buonarati O, Cook S, Goodell D, Chalmers N, Rumian N, Tullis J, et al.
Cell Rep . 2020 Jan; 30(1):1-8.e4. PMID: 31914378
DAPK1 binding to GluN2B was prominently reported to mediate ischemic cell death in vivo. DAPK1 and CaMKII bind to the same GluN2B region, and their binding is mutually exclusive. Here,...
4.
Cook S, Goodell D, Restrepo S, Arnold D, Bayer K
Cell Rep . 2019 Apr; 27(3):658-665.e4. PMID: 30995464
CaMKIIα is a central mediator of bidirectional synaptic plasticity, including long-term potentiation (LTP) and long-term depression (LTD). To study how CaMKIIα movement during plasticity is affected by soluble amyloid-β peptide...
5.
Woolfrey K, OLeary H, Goodell D, Robertson H, Horne E, Coultrap S, et al.
J Biol Chem . 2017 Dec; 293(5):1551-1567. PMID: 29196604
Both long-term potentiation (LTP) and depression (LTD) of excitatory synapse strength require the Ca/calmodulin (CaM)-dependent protein kinase II (CaMKII) and its autonomous activity generated by Thr-286 autophosphorylation. Additionally, LTP and...
6.
Goodell D, Zaegel V, Coultrap S, Hell J, Bayer K
Cell Rep . 2017 Jun; 19(11):2231-2243. PMID: 28614711
The death-associated protein kinase 1 (DAPK1) is a potent mediator of neuronal cell death. Here, we find that DAPK1 also functions in synaptic plasticity by regulating the Ca/calmodulin (CaM)-dependent protein...
7.
Goodell D, Ahern M, Baynard J, Wall V, Bland S
Behav Brain Res . 2016 Sep; 317:1-15. PMID: 27633556
Post-weaning social isolation (PSI) has been shown to increase aggressive behavior and alter medial prefrontal cortex (mPFC) function in social species such as rats. Here we developed a novel escapable...
8.
Goodell D, Benke T, Bayer K
J Neurophysiol . 2016 Aug; 116(5):2140-2151. PMID: 27535377
The Ca/calmodulin-dependent protein kinase II (CaMKII) is a major mediator of long-term potentiation (LTP) and depression (LTD), two opposing forms of synaptic plasticity underlying learning, memory and cognition. The heterozygous...
9.
Ahern M, Goodell D, Adams J, Bland S
Brain Res . 2015 Nov; 1630:120-33. PMID: 26562664
Early life adversity has been related to a number of psychological disorders including mood and other disorders that can manifest as inappropriate or aggressive responses to social challenges. The present...
10.
Barcomb K, Goodell D, Arnold D, Bayer K
J Neurochem . 2015 Jul; 135(4):666-73. PMID: 26212614
The Ca(2+) /calmodulin-dependent protein kinase II (CaMKII) forms 12meric holoenzymes. These holoenzymes cluster into larger aggregates within neurons under ischemic conditions and in vitro when ischemic conditions are mimicked. This...