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Dayalan Sampath

Explore the profile of Dayalan Sampath including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 175
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Recent Articles
1.
Sampath D, Zardeneta M, Akbari Z, Singer J, Gopalakrishnan B, Hurst D, et al.
bioRxiv . 2025 Feb; PMID: 39975179
Our previous studies showed that intravenous injections of the small non-coding RNA mir-20a-3p is neuroprotective for stroke in the acute phase and attenuates long-term cognitive impairment in middle-aged female rats....
2.
Sampath D, Zardeneta M, Sohrabji F
Stroke . 2023 Nov; 54(12):e503-e504. PMID: 38011233
No abstract available.
3.
Sampath D, Branyan T, Markowsky K, Gunda R, Samiya N, Obenaus A, et al.
Neurobiol Aging . 2023 Jun; 129:168-177. PMID: 37336171
Stroke is a major cause of death and disability worldwide and is also a leading cause of vascular dementia and Alzheimer's disease, with older women experiencing accelerated decline. Our previous...
4.
Fine-Raquet B, Manzella F, Joksimovic S, Dietz R, Orfila J, Sampath D, et al.
Exp Biol Med (Maywood) . 2023 Jun; 248(7):578-587. PMID: 37309730
Preclinical studies have established that neonatal exposure to contemporary sedative/hypnotic drugs causes neurotoxicity in the developing rodent and primate brains. Our group recently reported that novel neuroactive steroid (3β,5β,17β)-3-hydroxyandrostane-17-carbonitrile (3β-OH)...
5.
Stewart C, Branyan T, Sampath D, Sohrabji F
Curr Top Behav Neurosci . 2022 Mar; 62:287-308. PMID: 35332459
Stroke is the fifth leading cause of death and as healthcare intervention improves, the number of stroke survivors has also increased. Furthermore, there exists a subgroup of younger adults, who...
6.
Joksimovic S, Sampath D, Krishnan K, Covey D, Jevtovic-Todorovic V, Raol Y, et al.
Br J Anaesth . 2021 May; 127(3):435-446. PMID: 33972091
Background: We recently showed that a neurosteroid analogue, (3β,5β,17β)-3-hydroxyandrostane-17-carbonitrile (3β-OH), induced hypnosis in rats. The aim of the present study was to evaluate the hypnotic and anaesthetic potential of 3β-OH...
7.
Panta A, Montgomery K, Nicolas M, Mani K, Sampath D, Sohrabji F
Front Aging Neurosci . 2020 Nov; 12:586362. PMID: 33132904
Cognitive impairment and memory loss are commonly seen after stroke and a third of patients will develop signs of dementia a year after stroke. Despite a large number of studies...
8.
Raol Y, Joksimovic S, Sampath D, Matter B, Lam P, Kompella U, et al.
Neurosci Lett . 2020 Aug; 738:135324. PMID: 32860887
Background: The hyperpolarizing activity of γ-aminobutyric acid A (GABA) receptors depends on the intracellular chloride gradient that is developmentally regulated by the activity of the chloride extruder potassium (K) chloride...
9.
Manzella F, Joksimovic S, Orfila J, Fine B, Dietz R, Sampath D, et al.
Front Syst Neurosci . 2020 Jun; 14:26. PMID: 32528257
Exposure to sedative/hypnotic and anesthetic drugs, such as ketamine, during the critical period of synaptogenesis, causes profound neurotoxicity in the developing rodent and primate brains and is associated with poor...
10.
Sampath D, Lam P, Laoprasert M, Diaz M, Busquet N, White A, et al.
Pediatr Res . 2020 Jan; 88(2):202-208. PMID: 31896131
Background: Hypoxia-ischemia (HI) is the most common cause of brain injury in newborns and the survivors often develop cognitive and sensorimotor disabilities that undermine the quality of life. In the...