Davide Cittaro
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Explore the profile of Davide Cittaro including associated specialties, affiliations and a list of published articles.
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74
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3035
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Recent Articles
11.
Butti E, Cattaneo S, Bacigaluppi M, Cambiaghi M, Scotti G, Brambilla E, et al.
Nat Commun
. 2022 Dec;
13(1):7579.
PMID: 36482070
The adult brain retains over life endogenous neural stem/precursor cells (eNPCs) within the subventricular zone (SVZ). Whether or not these cells exert physiological functions is still unclear. In the present...
12.
Gritti I, Basso V, Rinchai D, Corigliano F, Pivetti S, Gaviraghi M, et al.
EMBO J
. 2022 Oct;
41(22):e108040.
PMID: 36215697
The ribonuclease DIS3 is one of the most frequently mutated genes in the hematological cancer multiple myeloma, yet the basis of its tumor suppressor function in this disease remains unclear....
13.
Gambacorta V, Beretta S, Ciccimarra M, Zito L, Giannetti K, Andrisani A, et al.
Cancer Discov
. 2022 Mar;
12(6):1449-1461.
PMID: 35255120
Significance: Loss of HLA class II expression represents a frequent mechanism of leukemia posttransplantation relapse. Here we identify PRC2 as the main epigenetic driver of this immune escape modality and...
14.
Morelli L, Giansanti V, Cittaro D
BMC Bioinformatics
. 2021 Dec;
22(1):576.
PMID: 34847879
Single cell profiling has been proven to be a powerful tool in molecular biology to understand the complex behaviours of heterogeneous system. The definition of the properties of single cells...
15.
Tedesco M, Giannese F, Lazarevic D, Giansanti V, Rosano D, Monzani S, et al.
Nat Biotechnol
. 2021 Oct;
40(2):235-244.
PMID: 34635836
Recent efforts have succeeded in surveying open chromatin at the single-cell level, but high-throughput, single-cell assessment of heterochromatin and its underlying genomic determinants remains challenging. We engineered a hybrid transposase...
16.
Trimarchi M, Bertazzoni G, Vinciguerra A, Pardini C, Simeoni F, Cittaro D, et al.
Medicina (Kaunas)
. 2021 Sep;
57(9).
PMID: 34577784
Background And Objectives: Cocaine users may present with positive antineutrophil cytoplasmic antibodies (ANCA) and severe midline destructive lesions (CIMDL) which are histologically characterized by massive apoptosis. However, histopathological and laboratory...
17.
Santoliquido B, Frenquelli M, Contadini C, Bestetti S, Gaviraghi M, Barbieri E, et al.
Life Sci Alliance
. 2021 Jun;
4(8).
PMID: 34187875
The oncogenic role of common fragile sites (CFS), focal and pervasive gaps in the cancer genome arising from replicative stress, remains controversial. Exploiting the TCGA dataset, we found that in...
18.
Ferrari S, Beretta S, Jacob A, Cittaro D, Albano L, Merelli I, et al.
Nat Protoc
. 2021 May;
16(6):2991-3025.
PMID: 34031609
Gene editing by engineered nucleases has revolutionized the field of gene therapy by enabling targeted and precise modification of the genome. However, the limited availability of methods for clonal tracking...
19.
Manfrini N, Mancino M, Miluzio A, Oliveto S, Balestra M, Calamita P, et al.
Cancer Res
. 2020 Sep;
80(21):4693-4706.
PMID: 32963011
Multiple myeloma is a plasma cell neoplasm characterized by the production of unfolded immunoglobulins, which cause endoplasmic reticulum (ER) stress and sensitivity to proteasome inhibition. The genomic landscape of multiple...
20.
Ferrari S, Jacob A, Beretta S, Unali G, Albano L, Vavassori V, et al.
Nat Biotechnol
. 2020 Jul;
38(11):1298-1308.
PMID: 32601433
Targeted gene editing in hematopoietic stem cells (HSCs) is a promising treatment for several diseases. However, the limited efficiency of homology-directed repair (HDR) in HSCs and the unknown impact of...