David Z Pan
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Explore the profile of David Z Pan including associated specialties, affiliations and a list of published articles.
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23
Citations
236
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Recent Articles
1.
Feng C, Gu J, Zhu H, Ning S, Tang R, Hlaing M, et al.
Nanophotonics
. 2024 Dec;
13(12):2193-2206.
PMID: 39634509
Optical neural networks (ONNs) are promising hardware platforms for next-generation neuromorphic computing due to their high parallelism, low latency, and low energy consumption. However, previous integrated photonic tensor cores (PTCs)...
2.
Gao Z, Zhang Z, He Z, Gu J, Pan D, Boning D
Opt Express
. 2024 Nov;
32(21):37585-37598.
PMID: 39573619
Optimization methods are frequently exploited in the design of silicon photonic devices. In this paper, we demonstrate that pushing the objective function to its minimum during optimization often results in...
3.
Pan D, Soulette C, Aggarwal A, Han D, van Buuren N, Wu P, et al.
Gut
. 2024 Oct;
74(4):628-638.
PMID: 39384203
Background: The impact of nucleos(t)ide analogues on intrahepatic viral burden and immune microenvironment in patients with chronic hepatitis B (CHB) is not clear. Objective: We aimed to characterise the effects...
4.
Lee S, Garske K, Arasu U, Kar A, Miao Z, Alvarez M, et al.
EBioMedicine
. 2024 Jul;
106:105232.
PMID: 38991381
Background: Abdominal obesity increases the risk for non-alcoholic fatty liver disease (NAFLD), now known as metabolic dysfunction-associated steatotic liver disease (MASLD). Methods: To elucidate the directional cell-type level biological mechanisms...
5.
Garske K, Kar A, Comenho C, Balliu B, Pan D, Bhagat Y, et al.
Nat Commun
. 2023 Jul;
14(1):4214.
PMID: 37452040
Obesity-induced adipose tissue dysfunction can cause low-grade inflammation and downstream obesity comorbidities. Although preadipocytes may contribute to this pro-inflammatory environment, the underlying mechanisms are unclear. We used human primary preadipocytes...
6.
Darci-Maher N, Alvarez M, Arasu U, Selvarajan I, Lee S, Pan D, et al.
EBioMedicine
. 2023 May;
92:104620.
PMID: 37224770
Background: Non-alcoholic fatty liver disease (NAFLD) is a fast-growing, underdiagnosed, epidemic. We hypothesise that obesity-related inflammation compromises adipose tissue functions, preventing efficient fat storage, and thus driving ectopic fat accumulation...
7.
Conway J, Pouryahya M, Gindin Y, Pan D, Carrasco-Zevallos O, Mountain V, et al.
Cell Rep Med
. 2023 Apr;
4(4):101016.
PMID: 37075704
Nonalcoholic steatohepatitis (NASH) is the most common chronic liver disease globally and a leading cause for liver transplantation in the US. Its pathogenesis remains imprecisely defined. We combined two high-resolution...
8.
Pan D, Odorizzi P, Schoenichen A, Abdelghany M, Chen S, Osinusi A, et al.
Commun Med (Lond)
. 2023 Jan;
3(1):2.
PMID: 36596885
Background: Remdesivir (RDV) is an intravenous antiviral with activity against SARS-CoV-2 for treatment of hospitalized COVID-19 patients with moderate-to-severe disease. Biomarkers associated with clinical outcomes have been identified for COVID-19,...
9.
Garske K, Comenho C, Pan D, Alvarez M, Mohlke K, Laakso M, et al.
Epigenetics
. 2022 Jun;
17(13):1849-1862.
PMID: 35746833
Obesity perturbs central functions of human adipose tissue, centred on differentiation of preadipocytes to adipocytes, i.e., adipogenesis. The large environmental component of obesity makes it important to elucidate epigenetic regulatory...
10.
Miao Z, Garske K, Pan D, Koka A, Kaminska D, Mannisto V, et al.
HGG Adv
. 2022 Jan;
3(1):100056.
PMID: 35047847
The prevalence of non-alcoholic fatty liver disease (NAFLD), now also known as metabolic dysfunction-associated fatty liver disease (MAFLD), is rapidly increasing worldwide due to the ongoing obesity epidemic. However, currently...