David Weaver
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Explore the profile of David Weaver including associated specialties, affiliations and a list of published articles.
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54
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2816
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Recent Articles
1.
Naghdi S, Mishra P, Roy S, Weaver D, Walter L, Davies E, et al.
Nat Commun
. 2025 Mar;
16(1):2416.
PMID: 40069152
Differences between normal tissues and invading tumors that allow tumor targeting while saving normal tissue are much sought after. Here we show that scarcity of VDAC2, and the consequent lack...
2.
Hasan P, Berezhnaya E, Rodriguez-Prados M, Weaver D, Bekeova C, Cartes-Saavedra B, et al.
Proc Natl Acad Sci U S A
. 2024 Aug;
121(35):e2402491121.
PMID: 39163336
Activating Ca-sensitive enzymes of oxidative metabolism while preventing calcium overload that leads to mitochondrial and cellular injury requires dynamic control of mitochondrial Ca uptake. This is ensured by the mitochondrial...
3.
Csordas G, Weaver D, Varnai P, Hajnoczky G
Contact (Thousand Oaks)
. 2024 Feb;
7:25152564241229273.
PMID: 38362008
Calcium signal propagation from endoplasmic reticulum (ER) to mitochondria regulates a multitude of mitochondrial and cell functions, including oxidative ATP production and cell fate decisions. Ca transfer is optimal at...
4.
Weaver D, Moyle B, McLennan C, Casali L
J Environ Manage
. 2023 Oct;
347:119136.
PMID: 37783088
Climate change is widely regarded as a "wicked problem" due to its complexity, interconnectedness, and the numerous stakeholders involved in finding a solution. The wickedness of climate change is further...
5.
Gal A, Balicza P, Weaver D, Naghdi S, Joseph S, Varnai P, et al.
EMBO Mol Med
. 2023 Jul;
15(8):e17911.
PMID: 37431817
No abstract available.
6.
Nichtova Z, Fernandez-Sanz C, De la Fuente S, Yuan Y, Hurst S, Lanvermann S, et al.
Circ Res
. 2023 Apr;
132(11):e171-e187.
PMID: 37057625
Background: Cardiac contractile function requires high energy from mitochondria, and Ca from the sarcoplasmic reticulum (SR). Via local Ca transfer at close mitochondria-SR contacts, cardiac excitation feedforward regulates mitochondrial ATP...
7.
Mvoula L, Skubic J, Weaver D, Betancourt-Garcia M
Cureus
. 2022 Dec;
14(10):e30941.
PMID: 36465751
Background: Traumatic rib fracture is a major cause of morbidity and mortality. Recent studies highlight the inadequacy of age and the number of rib fractures (NRFs) to assess patients' care...
8.
Katona M, Bartok A, Nichtova Z, Csordas G, Berezhnaya E, Weaver D, et al.
Nat Commun
. 2022 Nov;
13(1):6779.
PMID: 36351901
Endoplasmic reticulum-mitochondria contacts (ERMCs) are restructured in response to changes in cell state. While this restructuring has been implicated as a cause or consequence of pathology in numerous systems, the...
9.
Paillard M, Huang K, Weaver D, Lambert J, Elrod J, Hajnoczky G
Cell Calcium
. 2022 Jul;
105:102618.
PMID: 35779476
Heart failure (HF) is a leading cause of hospitalization and mortality worldwide. Yet, there is still limited knowledge on the underlying molecular mechanisms, because human tissue for research is scarce,...
10.
Timbrell S, Aglan H, Cramer A, Foden P, Weaver D, Pachter J, et al.
NPJ Breast Cancer
. 2021 May;
7(1):65.
PMID: 34050172
Cancer stem-like cells (CSC) contribute to therapy resistance and recurrence. Focal adhesion kinase (FAK) has a role in CSC regulation. We determined the effect of FAK inhibition on breast CSC...