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David W Leung

Explore the profile of David W Leung including associated specialties, affiliations and a list of published articles. Areas
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Citations 100
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Recent Articles
1.
Laabich A, Manmoto C, Kuksa V, Leung D, Vissvesvaran G, Karliga I, et al.
Exp Eye Res . 2007 Jun; 85(1):154-65. PMID: 17544396
The present study was performed to investigate the effect of flavonols, namely myricetin and structurally related quercetin and kaempferol against A2E and blue light-induced photoreceptors death in primary retinal cell...
2.
Leung D, Lindlief L, Laabich A, Vissvesvaran G, Kamat M, Lieu K, et al.
Invest Ophthalmol Vis Sci . 2007 Jan; 48(1):412-21. PMID: 17197562
Purpose: To determine whether minocycline, a compound known to protect the retina against light-induced damage in rodent models, and its structurally related analogues would protect photoreceptor cells in primary bovine...
3.
Laabich A, Vissvesvaran G, Lieu K, Murata K, McGinn T, Manmoto C, et al.
Invest Ophthalmol Vis Sci . 2006 Jun; 47(7):3156-63. PMID: 16799063
Purpose: The present study was performed to investigate the effect of crocin on blue light- and white light-induced rod and cone death in primary retinal cell cultures. Methods: Primary retinal...
4.
Hollenback D, Bonham L, Law L, Rossnagle E, Romero L, Carew H, et al.
J Lipid Res . 2005 Dec; 47(3):593-604. PMID: 16369050
Membranes of mammalian cells contain lysophosphatidic acid acyltransferase (LPAAT) activities that catalyze the acylation of sn-1-acyl lysophosphatidic acid (lysoPA) to form phosphatidic acid. As the biological roles and biochemical properties...
5.
Leung D, Tompkins C, Brewer J, Ball A, Coon M, Morris V, et al.
Mol Cancer . 2004 May; 3:15. PMID: 15140260
Background: The expression of the rodent phosphoinositide-specific phospholipase C delta-4 (PLCdelta4) has been found to be elevated upon mitogenic stimulation and expression analysis have linked the upregulation of PLCdelta4 expression...
6.
Bonham L, Leung D, White T, Hollenback D, Klein P, Tulinsky J, et al.
Expert Opin Ther Targets . 2003 Sep; 7(5):643-61. PMID: 14498826
Phosphatidic acid (PA) is a component of cellular membranes that is also a mediator of certain cell signalling functions associated with oncogenesis. These include ras/raf/Erk and Akt/mTor [1-3]. The authors...