David Vremec
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Explore the profile of David Vremec including associated specialties, affiliations and a list of published articles.
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40
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1625
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Recent Articles
1.
La Marca J, Aubrey B, Yang B, Chang C, Wang Z, Kueh A, et al.
Cell Death Differ
. 2023 Dec;
31(2):150-158.
PMID: 38097622
Whole-genome screens using CRISPR technologies are powerful tools to identify novel tumour suppressors as well as factors that impact responses of malignant cells to anti-cancer agents. Applying this methodology to...
2.
Biemond M, Vremec D, Gray D, Hodgkin P, Heinzel S
Immunol Cell Biol
. 2023 Dec;
102(2):117-130.
PMID: 38069638
Programmed death receptor 1 (PD-1) is an inhibitory receptor on T cells shown to restrain T-cell proliferation. PD-1 immune checkpoint blockade has emerged as a highly promising approach in cancer...
3.
Kato Y, Steiner T, Park H, Hitchcock R, Zaid A, Hor J, et al.
J Immunol
. 2020 Aug;
205(7):1842-1856.
PMID: 32839238
Follicular dendritic cells and macrophages have been strongly implicated in presentation of native Ag to B cells. This property has also occasionally been attributed to conventional dendritic cells (cDC) but...
4.
Vremec D
Methods Mol Biol
. 2016 May;
1423:61-87.
PMID: 27142009
Dendritic cells (DCs) form a complex network of cells that initiate and orchestrate immune responses against a vast array of pathogenic challenges. Developmentally and functionally distinct DC subtypes differentially regulate...
5.
6.
Carrington E, Zhang J, Sutherland R, Vikstrom I, Brady J, Soo P, et al.
Proc Natl Acad Sci U S A
. 2015 Mar;
112(13):4044-9.
PMID: 25775525
Dendritic cells (DCs) are heterogeneous, comprising subsets with functional specializations that play distinct roles in immunity as well as immunopathology. We investigated the molecular control of cell survival of two...
7.
Zhan Y, Carrington E, Ko H, Vikstrom I, Oon S, Zhang J, et al.
Arthritis Rheumatol
. 2014 Nov;
67(3):797-808.
PMID: 25418983
Objective: Interferon-α (IFNα)-producing plasmacytoid dendritic cells (PDCs) are implicated in the pathogenesis of systemic lupus erythematosus (SLE). IFNα-related genes are highlighted among SLE susceptibility alleles and are characteristically expressed in...
8.
Vremec D, Hansen J, Strasser A, Acha-Orbea H, Zhan Y, OKeeffe M, et al.
Mol Immunol
. 2014 Aug;
63(2):264-7.
PMID: 25081090
When mouse dendritic cells (DCs) are isolated from tissues, purified and placed in a nutritive culture they die more rapidly than would be expected from their normal turnover in vivo....
9.
Sathe P, Metcalf D, Vremec D, Naik S, Langdon W, Huntington N, et al.
Immunity
. 2014 Jul;
41(1):104-15.
PMID: 25035955
The relationship between dendritic cells (DCs) and macrophages is often debated. Here we ask whether steady-state, lymphoid-tissue-resident conventional DCs (cDCs), plasmacytoid DCs (pDCs), and macrophages share a common macrophage-DC-restricted precursor...
10.
Ko H, Brady J, Ryg-Cornejo V, Hansen D, Vremec D, Shortman K, et al.
J Immunol
. 2014 Feb;
192(5):2202-9.
PMID: 24489100
Although multiple dendritic cell (DC) subsets have the potential to induce Th17 differentiation in vitro, the key DC that is critical in Th17 induction and Th17-mediated disease remains moot. In...