Clive Meredith
Overview
Explore the profile of Clive Meredith including associated specialties, affiliations and a list of published articles.
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29
Citations
292
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Recent Articles
1.
Godec T, Crooks I, Scott K, Meredith C
Toxicol Rep
. 2019 Nov;
6:1155-1163.
PMID: 31737489
The mutagenic and genotoxic potential of Heated Tobacco Products (HTPs) has already been studied with the particulate phase and reported previously. This study has been designed to complement the assessment...
2.
Crooks I, Neilson L, Scott K, Reynolds L, Oke T, Forster M, et al.
Food Chem Toxicol
. 2018 Jun;
118:940-952.
PMID: 29879435
We designed a novel tobacco-heating product (THP) that heats tobacco to release nicotine and aerosolised components, such as glycerol and tobacco volatiles from a tobacco rod (Neostik). Heating tobacco significantly...
3.
McAdam K, Murphy J, Eldridge A, Meredith C, Proctor C
Regul Toxicol Pharmacol
. 2018 Mar;
95:102-114.
PMID: 29526814
The concept of a risk continuum for tobacco and nicotine products has been proposed, which differentiates products according to their propensity to reduce toxicant exposure and risk. Cigarettes are deemed...
4.
Fiebelkorn S, Meredith C
Risk Anal
. 2017 Dec;
38(7):1490-1501.
PMID: 29266361
Several epidemiological studies have demonstrated an association between occupational benzene exposure and increased leukemia risk, in particular acute myeloid leukemia (AML). However, there is still uncertainty as to the risk...
5.
Thorne D, Larard S, Baxter A, Meredith C, Gaa M
Toxicol Lett
. 2016 Dec;
265:170-178.
PMID: 27965004
DNA damage can be caused by a variety of external and internal factors and together with cellular responses, can establish genomic instability through multiple pathways. DNA damage therefore, is considered...
6.
Campbell J, Franzen A, Van Landingham C, Lumpkin M, Crowell S, Meredith C, et al.
Inhal Toxicol
. 2016 Aug;
28(11):520-35.
PMID: 27569524
Benzo[a]pyrene (BaP) is a by-product of incomplete combustion of fossil fuels and plant/wood products, including tobacco. A physiologically based pharmacokinetic (PBPK) model for BaP for the rat was extended to...
7.
Dalrymple A, Ordonez P, Thorne D, Walker D, Camacho O, Buttner A, et al.
Inhal Toxicol
. 2016 May;
28(7):324-38.
PMID: 27160659
Many laboratories are working to develop in vitro models that will replace in vivo tests, but occasionally there remains a regulatory expectation of some in vivo testing. Historically, cigarettes have...
8.
Thorne D, Dalrymple A, Dillon D, Duke M, Meredith C
Inhal Toxicol
. 2015 Sep;
27(12):629-40.
PMID: 26339773
This study describes the evaluation of a modified air-liquid interface BALB/c 3T3 cytotoxicity method for the assessment of smoke aerosols in vitro. The functionality and applicability of this modified protocol...
9.
Neilson L, Mankus C, Thorne D, Jackson G, DeBay J, Meredith C
Toxicol In Vitro
. 2015 Jul;
29(7):1952-62.
PMID: 26176715
Development of physiologically relevant test methods to analyse potential irritant effects to the respiratory tract caused by e-cigarette aerosols is required. This paper reports the method development and optimisation of...
10.
The mutagenic assessment of mainstream cigarette smoke using the Ames assay: a multi-strain approach
Thorne D, Kilford J, Hollings M, Dalrymple A, Ballantyne M, Meredith C, et al.
Mutat Res Genet Toxicol Environ Mutagen
. 2015 Apr;
782:9-17.
PMID: 25868126
Salmonella typhimurium strains TA1535, TA1537, TA97, TA102 and TA104 were assessed for their suitability and use in conjunction with a Vitrocell(®) VC 10 Smoking Robot and 3R4F reference mainstream cigarette...