Linsey E Haswell
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Explore the profile of Linsey E Haswell including associated specialties, affiliations and a list of published articles.
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14
Citations
416
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Recent Articles
1.
Tsolakos N, Haswell L, Miazzi F, Bishop E, Antoranz A, Pliaka V, et al.
Toxicol Rep
. 2024 May;
12:492-501.
PMID: 38774478
Cigarette smoking is a risk factor for several diseases such as cancer, cardiovascular disease (CVD), and chronic obstructive pulmonary diseases (COPD), however, the underlying mechanisms are not fully understood. Alternative...
2.
Haswell L, Gale N, Brown E, Azzopardi D, McEwan M, Thissen J, et al.
Intern Emerg Med
. 2023 May;
18(5):1359-1371.
PMID: 37249753
Electronic cigarette (EC) aerosol emissions generally contain fewer and lower concentrations of harmful and potentially harmful constituents, compared with cigarette smoke. Further studies are needed to establish whether decreased emissions...
3.
Azzopardi D, Haswell L, Frosina J, McEwan M, Gale N, Thissen J, et al.
Biomarkers
. 2022 Dec;
28(1):118-129.
PMID: 36484137
Oral nicotine pouches (NPs) are smokeless, tobacco-free products that have a potential role in tobacco harm reduction strategies. In a cross-sectional study in Sweden/Denmark, several recognised biomarkers of potential harm...
4.
Behrsing H, Wahab A, Ukishima L, Grodi C, Frentzel S, Johne S, et al.
Altern Lab Anim
. 2022 Aug;
50(4):293-309.
PMID: 35938181
The use of reconstituted human airway (RHuA) epithelial tissues to assess functional endpoints is highly relevant in respiratory toxicology, but standardised methods are lacking. In June 2015, the Institute for...
5.
Application of ToxTracker for the toxicological assessment of tobacco and nicotine delivery products
Smart D, Bozhilova S, Miazzi F, Haswell L, Gaca M, Thorne D, et al.
Toxicol Lett
. 2022 Jan;
358:59-68.
PMID: 35065211
Consumer demands and innovation have led to an increasingly diverse range of nicotine delivery systems, driven by a desire to reduce risk associated with traditional combustible cigarettes. This speed of...
6.
Haswell L, Smart D, Jaunky T, Baxter A, Santopietro S, Meredith S, et al.
Toxicol Lett
. 2021 Apr;
347:45-57.
PMID: 33892128
Goblet cell hyperplasia and overproduction of airway mucin are characteristic features of the lung epithelium of smokers and COPD patients. Tobacco heating products (THPs) are a potentially less risky alternative...
7.
Minet E, Haswell L, Corke S, Banerjee A, Baxter A, Verrastro I, et al.
Sci Rep
. 2021 Mar;
11(1):6091.
PMID: 33731770
Mucus hypersecretion contributes to lung function impairment observed in COPD (chronic obstructive pulmonary disease), a tobacco smoking-related disease. A detailed mucus hypersecretion adverse outcome pathway (AOP) has been constructed from...
8.
Haswell L, Corke S, Verrastro I, Baxter A, Banerjee A, Adamson J, et al.
Sci Rep
. 2018 Feb;
8(1):1145.
PMID: 29402904
The battery of regulatory tests used to evaluate the risk of novel tobacco products such as heated tobacco products (THPs) presents some limitations including a bias towards the apical endpoint...
9.
Haswell L, Baxter A, Banerjee A, Verrastro I, Mushonganono J, Adamson J, et al.
Sci Rep
. 2017 Apr;
7(1):888.
PMID: 28420881
Electronic cigarettes (e-cigarettes) use has increased globally and could potentially offer a lower risk alternative to cigarette smoking. Here, we assessed the transcriptional response of a primary 3D airway model...
10.
Azzopardi D, Haswell L, Foss-Smith G, Hewitt K, Asquith N, Corke S, et al.
Toxicol In Vitro
. 2015 Jun;
29(7):1720-8.
PMID: 26096598
In vitro toxicological studies for tobacco product assessment have traditionally been undertaken using the particulate phase of tobacco smoke. However, this does not truly reflect exposure conditions that occur in...