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David T W Wong

Explore the profile of David T W Wong including associated specialties, affiliations and a list of published articles. Areas
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Articles 146
Citations 4118
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Recent Articles
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Qian J, Xia J, Chiang S, Liu J, Li K, Li F, et al.
Sci Adv . 2025 Jan; 11(3):eadt5464. PMID: 39813350
Precise and rapid disease detection is critical for controlling infectious diseases like COVID-19. Current technologies struggle to simultaneously identify viral RNAs and host immune antibodies due to limited integration of...
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Mohammadi A, Chiang S, Li F, Wei F, Lau C, Aziz M, et al.
Sci Rep . 2024 Dec; 14(1):30792. PMID: 39730575
We developed a 4-parameter clinical assay using Electric Field Induced Release and Measurement (EFIRM) technology to simultaneously assess SARS-CoV-2 RNA (vRNA), nucleocapsid antigen, host binding (BAb) and neutralizing antibody (NAb)...
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Nichani P, Popovic M, Mihalache A, Pathak A, Muni R, Wong D, et al.
Ophthalmologica . 2024 Oct; 247(5-6):355-372. PMID: 39362194
Introduction: Intravitreal anti-vascular endothelial growth factor (VEGF) therapy has become the mainstay of treatment in many retinal diseases. The comparative efficacy and safety of newer bispecific anti-VEGF/angiopoietin 2 (Ang2) agents...
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Xia J, Wang Z, Becker R, Li F, Wei F, Yang S, et al.
ACS Nano . 2024 Aug; 18(33):22596-22607. PMID: 39132820
The isolation of viruses from complex biological samples is essential for creating sensitive bioassays that assess the efficacy and safety of viral therapeutics and vaccines, which have played a critical...
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Wang Z, Haslam D, Sawicki C, Rivas-Tumanyan S, Hu F, Liang L, et al.
J Am Heart Assoc . 2024 Jul; 13(15):e033350. PMID: 39023061
Background: Evidence from cohort studies indicates a bidirectional relationship between periodontal disease and type 2 diabetes (T2D), but the underlying mechanisms remain unknown. In this study, we aimed to (1)...
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Pandya B, Mihalache A, Hatamnejad A, Grad J, Popovic M, Wong D
Ophthalmologica . 2024 Jun; 247(4):261-274. PMID: 38857572
Introduction: The objective of this study was to examine the association between retinal thickness (RT) fluctuations and best corrected visual acuity (BCVA) in eyes with neovascular AMD, macular edema secondary...
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Cheng J, Swarup N, Morselli M, Huang W, Aziz M, Caggiano C, et al.
Nucleic Acids Res . 2024 May; 52(11):e50. PMID: 38797520
Whole-genome bisulfite sequencing (BS-Seq) measures cytosine methylation changes at single-base resolution and can be used to profile cell-free DNA (cfDNA). In plasma, ultrashort single-stranded cfDNA (uscfDNA, ∼50 nt) has been...
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Haslam D, Liang L, Guo K, Martinez-Lozano M, Perez C, Lee C, et al.
Diabetologia . 2024 May; 67(9):1838-1852. PMID: 38772919
Aims/hypothesis: Many studies have examined the relationship between plasma metabolites and type 2 diabetes progression, but few have explored saliva and multi-fluid metabolites. Methods: We used LC/MS to measure plasma...