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David Sidransky

Explore the profile of David Sidransky including associated specialties, affiliations and a list of published articles. Areas
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Articles 385
Citations 16097
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Recent Articles
1.
Madan E, Palma A, Vudatha V, Kumar A, Bhoopathi P, Wilhelm J, et al.
Nat Biotechnol . 2024 Dec; PMID: 39653752
Cell competition and fitness comparison between cancer and tumor microenvironment (TME) cells determine oncogenic fate. Our previous study established a role for human Flower isoforms as fitness fingerprints, where the...
2.
Sadhukhan P, Feng M, Illingworth E, Illingworth E, Sloma I, Ooki A, et al.
J Clin Invest . 2024 Dec; 135(2. PMID: 39630608
The Hippo signaling pathway plays a key role in tumorigenesis in different cancer types. We investigated the role of the Hippo effector YAP1 in the tumor immune microenvironment (TIME) of...
3.
Zamuner F, Ramos-Lopez A, Garcia-Negron A, Purcell-Wiltz A, Cortes-Ortiz A, Cuevas A, et al.
Biomed Rep . 2024 Jun; 21(2):112. PMID: 38912171
Late-stage cancers lack effective treatment, underscoring the need for early diagnosis to improve prognosis and decrease mortality rates. Molecular markers, such as DNA methylation, offer promise in early cancer detection....
4.
Purcell-Wiltz A, Zamuner F, Caraballo K, De Jesus L, Miranda Y, Ortiz D, et al.
Immun Inflamm Dis . 2024 Jun; 12(6):e1285. PMID: 38888444
As the SARS-CoV-2 virus spread throughout the world, millions of positive cases of COVID-19 were registered and, even though there are millions of people already vaccinated against SARS-CoV-2, a large...
5.
Danilov A, Flinn I, Davids M, Gregory B, Bentur O, Sidransky D, et al.
Haematologica . 2024 May; 109(10):3379-3382. PMID: 38813715
No abstract available.
6.
Rivera-Pena B, Folawiyo O, Turaga N, Rodriguez-Benitez R, Felici M, Aponte-Ortiz J, et al.
Oncol Lett . 2024 Jan; 27(3):89. PMID: 38268779
Differentially methylated regions (DMRs) can be used as head and neck squamous cell carcinoma (HNSCC) diagnostic, prognostic and therapeutic targets in precision medicine workflows. DNA from 21 HNSCC and 10...
7.
Mangalaparthi K, Patel K, Khan A, Nair B, Kumar R, Prasad T, et al.
Cancers (Basel) . 2023 Jul; 15(13). PMID: 37444412
Esophageal squamous cell carcinoma (ESCC) is a heterogeneous cancer associated with a poor prognosis in advanced stages. In India, it is the sixth most common cause of cancer-related mortality. In...
8.
Terzo E, Apte S, Padhye S, Rashed S, Austin W, Caponegro M, et al.
Cancer Res Commun . 2023 Jun; 3(6):969-979. PMID: 37377612
Significance: This study demonstrates that ribosome heterogeneity in cancer can be exploited to develop selective ribogenesis inhibitors. The colorectal cancer CMS2 subtype, with a high unmet need for therapeutics, shows...
9.
Peace D, Izumchenko E, Sidransky D
Nat Genet . 2023 Apr; 55(4):534-535. PMID: 37016098
No abstract available.
10.
Ghantous Y, Nashef A, Sidransky D, AbdelRaziq M, Alkeesh K, Araidy S, et al.
Cancers (Basel) . 2022 Oct; 14(19). PMID: 36230555
Objectives: The most notable changes in the eighth edition of the AJCC Cancer Staging System include incorporating the depth of invasion (DOI) into T staging and extranodal extension (ENE) into...