David Sheikh-Hamad
Overview
Explore the profile of David Sheikh-Hamad including associated specialties, affiliations and a list of published articles.
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59
Citations
1562
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Recent Articles
1.
Wu Y, Lee T, Cheng O, Peden E, Peden E, Li Q, et al.
J Am Soc Nephrol
. 2025 Jan;
PMID: 39883520
No abstract available.
2.
Abdel-Rahman E, Hasan I, Abdelrazeq A, Rawabdeh A, Liu M, Ghahramani N, et al.
Kidney Int Rep
. 2025 Jan;
10(1):54-74.
PMID: 39810788
Chronic kidney disease (CKD), a major global public health problem, emerged as one of the leading causes of death, affecting over 800 million individuals worldwide, with significant burden to patients...
3.
4.
Hudson C, Roy A, Li Q, Joshi A, Yin T, Kumar A, et al.
Am J Physiol Renal Physiol
. 2024 May;
327(1):F137-F145.
PMID: 38779756
Polymyxins are a last-resort treatment option for multidrug-resistant gram-negative bacterial infections, but they are associated with nephrotoxicity. Gelofusine was previously shown to reduce polymyxin-associated kidney injury in an animal model....
5.
Holliday Jr M, Majeti R, Sheikh-Hamad D
Clin J Am Soc Nephrol
. 2023 Sep;
19(4):538-545.
PMID: 37678249
Chronic interstitial nephritis in agricultural communities (CINAC) is an epidemic of kidney disease affecting specific tropical and subtropical regions worldwide and is characterized by progressive CKD in the absence of...
6.
Nanocurcumin combined with insulin alleviates diabetic kidney disease through P38/P53 signaling axis
Ganugula R, Nuthalapati N, Dwivedi S, Zou D, Arora M, Friend R, et al.
J Control Release
. 2022 Dec;
353:621-633.
PMID: 36503070
Treatments for diabetic kidney disease (DKD) mainly focus on managing hyperglycemia and hypertension, but emerging evidence suggests that inflammation also plays a role in the pathogenesis of DKD. This 10-week...
7.
Holliday Jr M, Li Q, Bustamante E, Niu J, Huang L, Espina I, et al.
Clin J Am Soc Nephrol
. 2022 Aug;
17(9):1293-1304.
PMID: 35944911
Background And Objectives: The etiology of chronic kidney disease of unclear etiology, also known as Mesoamerican nephropathy, remains unclear. We investigated potential etiologies for Mesoamerican nephropathy in an immigrant dialysis...
8.
Sheikh-Hamad D, Holliday M, Li Q
J Cell Immunol
. 2022 Jan;
3(6):364-369.
PMID: 35098216
The multi-ligand binding protein megalin (LRP2) is ubiquitously expressed and facilitates cell uptake of hormones, nutrients and vitamins. We have recently shown megalin is present in the mitochondria of cultured...
9.
Li Q, Holliday M, Pan J, Tan L, Li J, Sheikh-Hamad D
Lab Invest
. 2022 Jan;
102(5):534-544.
PMID: 35046485
The mitochondrial intracrine Stanniocalcin 1 (STC1) activates mitochondrial anti-oxidant defenses. LRP2 (megalin) shuttles STC1 to the mitochondria through retrograde early endosome-to-Golgi- and Rab32-mediated pathway, and LRP2 KO impairs mitochondrial respiration...
10.
Sheikh-Hamad D
Am J Physiol Renal Physiol
. 2021 Aug;
321(3):F355.
PMID: 34460353
No abstract available.