David Schlessinger
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Explore the profile of David Schlessinger including associated specialties, affiliations and a list of published articles.
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254
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35541
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Recent Articles
11.
Yao Y, Yang R, Zhu J, Schlessinger D, Sima J
Cell Biosci
. 2023 Jul;
13(1):128.
PMID: 37430358
Background: Ectodysplasin-A (EDA), a skin-specific TNF ligand, interacts with its membrane receptor EDAR to trigger EDA signaling in skin appendage formation. Gene mutations in EDA signaling cause Anhidrotic/Hypohidrotic Ectodermal Dysplasia...
12.
Effect of Genetic Factors, Age and Sex on Levels of Circulating Extracellular Vesicles and Platelets
Orru V, Virdis F, Marongiu M, Serra V, Schlessinger D, Devoto M, et al.
Int J Mol Sci
. 2023 Apr;
24(8).
PMID: 37108346
Extracellular vesicles (EVs) mediate cell interactions in biological processes, such as receptor activation or molecule transfer. Estimates of variation by age and sex have been limited by small sample size,...
13.
Liskovykh M, Petrov N, Noskov V, Masumoto H, Earnshaw W, Schlessinger D, et al.
Cell Mol Life Sci
. 2023 Apr;
80(5):121.
PMID: 37043028
Although they are organelles without a limiting membrane, nucleoli have an exclusive structure, built upon the rDNA-rich acrocentric short arms of five human chromosomes (nucleolar organizer regions or NORs). This...
14.
Tarasewicz D, Karter A, Pimentel N, Moffet H, Thai K, Schlessinger D, et al.
Diabetes Care
. 2023 Mar;
46(5):1068-1075.
PMID: 36930723
Objective: Although diabetic retinopathy is a leading cause of blindness worldwide, diabetes-related blindness can be prevented through effective screening, detection, and treatment of disease. The study goal was to develop...
15.
Zajac G, Gagliano Taliun S, Sidore C, Graham S, Asvold B, Brumpton B, et al.
Genet Epidemiol
. 2023 Feb;
47(3):231-248.
PMID: 36739617
Linkage analysis, a class of methods for detecting co-segregation of genomic segments and traits in families, was used to map disease-causing genes for decades before genotyping arrays and dense SNP...
16.
Oppong R, Terracciano A, Picard M, Qian Y, Butler T, Tanaka T, et al.
Elife
. 2022 Dec;
11.
PMID: 36537669
Background: Mitochondrial DNA copy number (mtDNAcn) in tissues and blood can be altered in conditions like diabetes and major depression and may play a role in aging and longevity. However,...
17.
Alghatrif M, Lakatta E, Morrell C, Fegatelli D, Fiorillo E, Marongiu M, et al.
Geroscience
. 2022 Dec;
45(2):1001-1013.
PMID: 36520341
Hypertrophic carotid geometric phenotypes (h-CGP) are predictors of incident cardiovascular disease (CVD). While arterial aging is hypothesized as a contributor to this associated risk, the association of CGPs with chronological...
18.
Neeman E, Liu V, Mishra P, Thai K, Xu J, Clancy H, et al.
JAMA Netw Open
. 2022 Nov;
5(11):e2240373.
PMID: 36409498
Importance: While hospital-associated venous thromboembolism (HA-VTE) is a known complication of hospitalization, contemporary incidence and outcomes data are scarce and methodologically contested. Objective: To define and validate an automated electronic...
19.
Rose C, Thombley R, Noshad M, Lu Y, Clancy H, Schlessinger D, et al.
J Am Med Inform Assoc
. 2022 Oct;
30(1):8-15.
PMID: 36303451
Objective: To determine whether novel measures of contextual factors from multi-site electronic health record (EHR) audit log data can explain variation in clinical process outcomes. Materials And Methods: We selected...
20.
Serra R, Rallo V, Pinna A, Steri M, Piras M, Marongiu M, et al.
Graefes Arch Clin Exp Ophthalmol
. 2022 Oct;
261(3):691-698.
PMID: 36264335
Purpose: To ascertain the prevalence and clinical and genetic features of age-related macular degeneration (AMD) in subjects living in the Lanusei valley, Central Sardinia, Italy, involved in a study on...