David S Ziegler
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Explore the profile of David S Ziegler including associated specialties, affiliations and a list of published articles.
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147
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3120
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Recent Articles
11.
Mazariego C, Daly R, McGill B, Kelada L, McKay S, Hetherington K, et al.
Pediatr Blood Cancer
. 2024 Aug;
71(11):e31147.
PMID: 39185694
Introduction: Accessing compassionate access schemes to obtain novel therapeutic agents for children with hard-to-treat cancers can be fraught with challenges such as regulatory barriers and limited resources. This study aimed...
12.
Hansford J, Bouche G, Ramaswamy V, Jabado N, Fonseca A, Moloney S, et al.
J Clin Oncol
. 2024 Aug;
42(35):4126-4129.
PMID: 39110925
Our international team highlights issues with efficacy reports in several studies on DMG with the new drug ONC201.
13.
Robertson E, Hetherington K, Daly R, Donoghoe M, Handelsman N, Ziegler D, et al.
Cancer Med
. 2024 Jun;
13(12):e7339.
PMID: 38898768
Background: Patient-reported outcomes measures (PROMs) are increasingly being collected within cancer clinical trials, yet limited literature on the feasibility and acceptability of doing so. Methods: We collected parent-proxy and adolescent...
14.
Liver disease and transplantation in telomere biology disorders: An international multicenter cohort
Wang Y, Kaj-Carbaidwala B, Lane A, Agarwal S, Beier F, Bertuch A, et al.
Hepatol Commun
. 2024 Jun;
8(7).
PMID: 38896081
Background: Patients with telomere biology disorders (TBD) develop hepatic disease, including hepatitis, cirrhosis, and hepatopulmonary syndrome. No specific treatment exists for TBD-related liver disease, and the role of liver transplantation...
15.
Lau L, Khuong-Quang D, Mayoh C, Wong M, Barahona P, Ajuyah P, et al.
Nat Med
. 2024 Jun;
30(7):1913-1922.
PMID: 38844796
Recent research showed that precision medicine can identify new treatment strategies for patients with childhood cancers. However, it is unclear which patients will benefit most from precision-guided treatment (PGT). Here...
16.
Valvi S, Manoharan N, Mateos M, Hassall T, Ziegler D, McCowage G, et al.
Med J Aust
. 2024 May;
220(10):533-538.
PMID: 38699949
Introduction: The main mission of the Australian and New Zealand Children's Haematology and Oncology Group (ANZCHOG) is to develop and facilitate local access to the world's leading evidence-based clinical trials...
17.
Upton D, Ziegler D, Tsoli M
Methods Mol Biol
. 2024 Apr;
2806:75-90.
PMID: 38676797
The development of clinically relevant and reliable models of central nervous system tumors has been instrumental in advancing the field of Neuro-Oncology. The orthotopic intracranial injection is widely used to...
18.
Mazariego C, McKay S, Tyedmers E, Kelada L, McGill B, Daly R, et al.
Front Med (Lausanne)
. 2024 Apr;
11:1332434.
PMID: 38606155
Objectives: Paediatric oncologists often encounter challenges when seeking compassionate access to off-label therapies for their patients. This study employed implementation science and co-design techniques to develop the ProCure medicines database,...
19.
Ercan A, Aronson M, Fernandez N, Chang Y, Levine A, Liu Z, et al.
Lancet Oncol
. 2024 Mar;
25(5):668-682.
PMID: 38552658
Background: Constitutional mismatch repair deficiency (CMMRD) syndrome is a rare and aggressive cancer predisposition syndrome. Because a scarcity of data on this condition contributes to management challenges and poor outcomes,...
20.
Chen Y, Khan A, Katsinas C, Michniewicz F, Goldberg J, Franshaw L, et al.
Neurooncol Adv
. 2024 Mar;
6(1):vdae029.
PMID: 38550394
Background: Diffuse intrinsic pontine gliomas (DIPGs) pose a significant challenge as a highly aggressive and currently incurable form of pediatric brain cancer, necessitating the development of novel therapeutic strategies. Omacetaxine,...