David S Siscovick
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Explore the profile of David S Siscovick including associated specialties, affiliations and a list of published articles.
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33194
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Recent Articles
21.
Cronje H, Mi M, Austin T, Biggs M, Siscovick D, Lemaitre R, et al.
Diabetes
. 2023 Feb;
72(5):666-673.
PMID: 36749929
Article Highlights: Plasma proteins are associated with the risk of incident diabetes in older adults independent of various demographic, lifestyle, and biochemical risk factors. These same proteins are associated with...
22.
Ong K, Marklund M, Huang L, Rye K, Hui N, Pan X, et al.
BMJ
. 2023 Jan;
380:e072909.
PMID: 36653033
Objective: To assess the prospective associations of circulating levels of omega 3 polyunsaturated fatty acid (n-3 PUFA) biomarkers (including plant derived α linolenic acid and seafood derived eicosapentaenoic acid, docosapentaenoic...
23.
Pellegrini C, Buzkova P, Oesterle A, Heckbert S, Tracy R, Siscovick D, et al.
Heart
. 2022 Dec;
109(8):606-611.
PMID: 36549682
Objective: Obesity and dysmetabolism are major risk factors for atrial fibrillation (AF). Fasting and postload levels of glucose and non-esterified fatty acids (NEFAs) reflect different facets of metabolic regulation. We...
24.
Oesterle A, Buzkova P, Pellegrini C, Hirsch C, Tracy R, Siscovick D, et al.
J Gerontol A Biol Sci Med Sci
. 2022 Nov;
78(7):1164-1171.
PMID: 36373954
Background: Glucose and non-esterified fatty acids (NEFA) are myocardial fuels whose fasting and post-prandial levels are under different homeostatic regulation. The relationships of fasting and post-load glucose and NEFA with...
25.
de Oliveira Otto M, Li X, Wang Z, Siscovick D, Newman A, Lai H, et al.
J Alzheimers Dis
. 2022 Sep;
89(4):1439-1452.
PMID: 36057823
Background: Animal studies suggest that gut microbiome metabolites such as trimethylamine N-oxide (TMAO) may influence cognitive function and dementia risk. However potential health effects of TMAO and related metabolites remain...
26.
Jensen P, Fretts A, Hoofnagle A, McKnight B, Howard B, Umans J, et al.
Cardiovasc Diabetol
. 2022 Aug;
21(1):167.
PMID: 36042511
Background: Plasma ceramides and sphingomyelins have been independently linked to diabetes risk, glucose and insulin levels, and the risk of several cardiovascular (CVD) outcomes. However, whether individual ceramide and sphingomyelin...
27.
Lemaitre R, Jensen P, Zeigler M, Fretts A, Umans J, Howard B, et al.
EBioMedicine
. 2022 Aug;
83:104189.
PMID: 35930887
Background: Epoxyeicosatrienoic acids (EETs) are metabolites of arachidonic acid that may impact atherosclerosis, and animal experimental studies suggest EETs protect cardiac function. Plasma EETs are mostly esterified to phospholipids and...
28.
Wang M, Wang Z, Lee Y, Lai H, de Oliveira Otto M, Lemaitre R, et al.
Arterioscler Thromb Vasc Biol
. 2022 Aug;
42(9):e273-e288.
PMID: 35912635
Background: Effects of animal source foods (ASF) on atherosclerotic cardiovascular disease (ASCVD) and underlying mechanisms remain controversial. We investigated prospective associations of different ASF with incident ASCVD and potential mediation...
29.
Lamprea-Montealegre J, Arnold A, McClelland R, Mukamal K, Djousse L, Biggs M, et al.
J Am Heart Assoc
. 2022 Jul;
11(15):e024012.
PMID: 35904195
Background Advanced glycation endproducts (AGEs) have been linked to cardiovascular disease (CVD) in cohorts with and without diabetes. Data are lacking on prospective associations of various α-dicarbonyl-derived AGEs and incident...
30.
Austin T, McHugh C, Brody J, Bis J, Sitlani C, Bartz T, et al.
Eur J Epidemiol
. 2022 Jul;
37(7):755-765.
PMID: 35790642
Background: In the last decade, genomic studies have identified and replicated thousands of genetic associations with measures of health and disease and contributed to the understanding of the etiology of...