David S Siscovick
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Explore the profile of David S Siscovick including associated specialties, affiliations and a list of published articles.
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33194
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Recent Articles
11.
Bockus L, Jensen P, Fretts A, Hoofnagle A, McKnight B, Sitlani C, et al.
JAMA Netw Open
. 2023 Nov;
6(11):e2343854.
PMID: 37976059
Importance: Sphingolipids, including ceramides and sphingomyelins, may influence the pathophysiology and risk of sudden cardiac death (SCD) through multiple biological activities. Whether the length of the fatty acid acylated to...
12.
Garg P, Guan W, Nomura S, Weir N, Tintle N, Virtanen J, et al.
Am J Clin Nutr
. 2023 Sep;
118(5):921-929.
PMID: 37769813
Background: The presence of atrial fibrillation (AF) is associated with an over 2-fold increased risk of stroke, heart failure, and cardiovascular mortality. Long chain n-6 PUFAs have been suggested to...
13.
de Oliveira Otto M, Wu J, Thacker E, Lai H, Lemaitre R, Padhye N, et al.
J Alzheimers Dis
. 2023 Aug;
95(3):965-979.
PMID: 37638432
Background: Comprising nearly 35% of brain lipids, polyunsaturated fatty acids (PUFA) are essential for optimal brain function. However, the role of PUFA on cognitive health outcomes later in life is...
14.
Lidgard B, Bansal N, Zelnick L, Hoofnagle A, Fretts A, Longstreth Jr W, et al.
EBioMedicine
. 2023 Aug;
95:104765.
PMID: 37634384
Background: Sphingolipids are a family of circulating lipids with regulatory and signaling roles that are strongly associated with both eGFR and cardiovascular disease. Patients with chronic kidney disease (CKD) are...
15.
Lemaitre R, Jensen P, Wang Z, Fretts A, Sitlani C, Nemet I, et al.
J Am Heart Assoc
. 2023 Aug;
12(16):e8711.
PMID: 37581385
Background The association of circulating trimethylamine--oxide (TMAO) with stroke has received limited attention. To address this gap, we examined the associations of serial measures of plasma TMAO with incident ischemic...
16.
Qian F, Tintle N, Jensen P, Lemaitre R, Imamura F, Feldreich T, et al.
J Am Coll Cardiol
. 2023 Jul;
82(4):336-349.
PMID: 37468189
Background: The relationship between omega-3 fatty acids and atrial fibrillation (AF) remains controversial. Objectives: This study aimed to determine the prospective associations of blood or adipose tissue levels of eicosapentaenoic...
17.
Fretts A, Siscovick D, Malloy K, Sitlani C, Navas-Acien A, Zhang Y, et al.
JAMA Netw Open
. 2023 May;
6(5):e2311476.
PMID: 37140924
Importance: To our knowledge, no published studies have investigated the association of ambulatory activity with risk of death among young and middle-aged American Indian individuals. The burden of chronic disease...
18.
Ginsberg C, Hoofnagle A, Katz R, Cheng J, Hsu S, Budoff M, et al.
Circ Cardiovasc Imaging
. 2023 Mar;
16(3):e015055.
PMID: 36943910
No abstract available.
19.
Wang M, Li X, Wang Z, de Oliveira Otto M, Lemaitre R, Fretts A, et al.
Eur Heart J
. 2023 Mar;
44(18):1608-1618.
PMID: 36883587
Aims: Little is known about associations of trimethylamine N-oxide (TMAO), a novel gut microbiota-generated metabolite of dietary phosphatidylcholine and carnitine, and its changes over time with all-cause and cause-specific mortality...
20.
Lovasi G, Boise S, Jogi S, Hurvitz P, Rundle A, Diez J, et al.
Am J Prev Med
. 2023 Mar;
64(6):877-887.
PMID: 36882344
Introduction: Natural experiments can strengthen evidence linking neighborhood food retail presence to dietary intake patterns and cardiometabolic health outcomes, yet sample size and follow-up duration are typically not extensive. To...