David S Palmer
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Explore the profile of David S Palmer including associated specialties, affiliations and a list of published articles.
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56
Citations
674
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Recent Articles
1.
Christie L, Rutherford S, Palmer D, Baker M, Butler H
Front Bioeng Biotechnol
. 2024 Jun;
12:1349473.
PMID: 38863496
Pharmaceutical manufacturing is reliant upon bioprocessing approaches to generate the range of therapeutic products that are available today. The high cost of production, susceptibility to process failure, and requirement to...
2.
Bradley E, Fusani L, Chung C, Craggs P, Demont E, Humphreys P, et al.
J Med Chem
. 2023 Nov;
66(23):15728-15749.
PMID: 37967462
Small-molecule-mediated disruption of the protein-protein interactions between acetylated histone tails and the tandem bromodomains of the bromodomain and extra-terminal (BET) family of proteins is an important mechanism of action for...
3.
Cameron J, Sala A, Antoniou G, Brennan P, Butler H, Conn J, et al.
Br J Cancer
. 2023 Sep;
129(10):1658-1666.
PMID: 37717120
Background: A rapid, low-cost blood test that can be applied to reliably detect multiple different cancer types would be transformational. Methods: In this large-scale discovery study (n = 2092 patients)...
4.
Sala A, Cameron J, Brennan P, Crosbie E, Curran T, Gray E, et al.
J Exp Clin Cancer Res
. 2023 Aug;
42(1):207.
PMID: 37580713
The advances in cancer research achieved in the last 50 years have been remarkable and have provided a deeper knowledge of this disease in many of its conceptual and biochemical...
5.
McHardy R, Antoniou G, Conn J, Baker M, Palmer D
Analyst
. 2023 Jul;
148(16):3860-3869.
PMID: 37435822
Over recent years, deep learning (DL) has become more widely used within the field of cancer diagnostics. However, DL often requires large training datasets to prevent overfitting, which can be...
6.
Antoniou G, Conn J, Smith B, Brennan P, Baker M, Palmer D
Analyst
. 2023 Mar;
148(8):1770-1776.
PMID: 36967685
Attenuated total reflectance (ATR)-Fourier transform infrared (FTIR) spectroscopy alongside machine learning (ML) techniques is an emerging approach for the early detection of brain cancer in clinical practice. A crucial step...
7.
Fowles D, Palmer D
Phys Chem Chem Phys
. 2023 Feb;
25(9):6944-6954.
PMID: 36806875
Simultaneous calculation of entropies, enthalpies and free energies has been a long-standing challenge in computational chemistry, partly because of the difficulty in obtaining estimates of all three properties from a...
8.
Connal S, Cameron J, Sala A, Brennan P, Palmer D, Palmer J, et al.
J Transl Med
. 2023 Feb;
21(1):118.
PMID: 36774504
Cancer is a worldwide pandemic. The burden it imposes grows steadily on a global scale causing emotional, physical, and financial strains on individuals, families, and health care systems. Despite being...
9.
Conn J, Carter J, Conn J, Subramanian V, Baxter A, Engkvist O, et al.
J Chem Inf Model
. 2023 Feb;
63(4):1099-1113.
PMID: 36758178
Accurate methods to predict solubility from molecular structure are highly sought after in the chemical sciences. To assess the state of the art, the American Chemical Society organized a "Second...
10.
Sala A, Cameron J, Jenkins C, Barr H, Christie L, Conn J, et al.
Cancers (Basel)
. 2022 Jul;
14(13).
PMID: 35804820
Pancreatic cancer claims over 460,000 victims per year. The carbohydrate antigen (CA) 19-9 test is the blood test used for pancreatic cancer's detection; however, its levels can be raised in...