David S Burz
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Explore the profile of David S Burz including associated specialties, affiliations and a list of published articles.
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40
Citations
1076
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Recent Articles
1.
Yu J, Ramirez L, Lin Q, Burz D, Shekhtman A
J Phys Chem B
. 2024 Jul;
128(29):7002-7021.
PMID: 39012038
Ribosomes bind to many metabolic enzymes and change their activity. A general mechanism for ribosome-mediated amplification of metabolic enzyme activity, RAMBO, was formulated and elucidated for the glycolytic enzyme triosephosphate...
2.
Theophall G, Ramirez L, Premo A, Reverdatto S, Manigrasso M, Yepuri G, et al.
J Biol Chem
. 2023 Oct;
299(11):105342.
PMID: 37832872
The diaphanous-related formin, Diaphanous 1 (DIAPH1), is required for the assembly of Filamentous (F)-actin structures. DIAPH1 is an intracellular effector of the receptor for advanced glycation end products (RAGE) and...
3.
Sciolino N, Reverdatto S, Premo A, Breindel L, Yu J, Theophall G, et al.
Sci Rep
. 2022 Dec;
12(1):22293.
PMID: 36566335
Analytical tools to study cell physiology are critical for optimizing drug-host interactions. Real time pulse chase NMR spectroscopy, RTPC-NMR, was introduced to monitor the kinetics of metabolite production in HEK...
4.
Sciolino N, Liu A, Breindel L, Burz D, Sulchek T, Shekhtman A
Commun Biol
. 2022 Jul;
5(1):673.
PMID: 35798845
No abstract available.
5.
Sciolino N, Liu A, Breindel L, Burz D, Sulchek T, Shekhtman A
Commun Biol
. 2022 May;
5(1):451.
PMID: 35551287
High-resolution structural studies of proteins and protein complexes in a native eukaryotic environment present a challenge to structural biology. In-cell NMR can characterize atomic resolution structures but requires high concentrations...
6.
Yu J, Ramirez L, Premo A, Busch D, Lin Q, Burz D, et al.
Biochemistry
. 2021 Jun;
60(24):1885-1895.
PMID: 34081430
NMR spectroscopy was used to investigate the phenomenon of ribosome-amplified metabolism or RAMBO between pyruvate kinase and ribosomes. Because the concentration of ribosomes increases as the cell grows, ribosome binding...
7.
Breindel L, Burz D, Shekhtman A
Commun Biol
. 2020 May;
3(1):249.
PMID: 32439966
Protein-protein interactions, PPIs, underlie most cellular processes, but many PPIs depend on a particular metabolic state that can only be observed in live, actively metabolizing cells. Real time in-cell NMR...
8.
Breindel L, Yu J, Burz D, Shekhtman A
PLoS One
. 2020 Apr;
15(4):e0232015.
PMID: 32330166
Transient, site-specific, or so-called quinary, interactions are omnipresent in live cells and modulate protein stability and activity. Quinary intreactions are readily detected by in-cell NMR spectroscopy as severe broadening of...
9.
Burz D, Breindel L, Shekhtman A
Methods Enzymol
. 2019 May;
621:305-328.
PMID: 31128785
In-cell NMR spectroscopy is a powerful tool to study protein structures and interactions under near physiological conditions in both prokaryotic and eukaryotic living cells. The low sensitivity and resolution of...
10.
Burz D, Breindel L, Shekhtman A
Int J Mol Sci
. 2019 Mar;
20(6).
PMID: 30875837
The effects of RNA on in-cell NMR spectroscopy and ribosomes on the kinetic activity of several metabolic enzymes are reviewed. Quinary interactions between labelled target proteins and RNA broaden in-cell...