Alexander Shekhtman
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Explore the profile of Alexander Shekhtman including associated specialties, affiliations and a list of published articles.
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110
Citations
2202
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Recent Articles
1.
Ramasamy R, Shekhtman A, Schmidt A
Atherosclerosis
. 2024 Nov;
:117304.
PMID: 39492058
Background And Aims: In hyperglycemia, inflammation, oxidative stress and aging, Damage Associated Molecular Patterns (DAMPs) accumulate in conditions such as atherosclerosis. Binding of DAMPs to receptors such as the receptor...
2.
Menon R, Yepuri G, Martel D, Quadri N, Hasan S, Manigrasso M, et al.
NMR Biomed
. 2024 Oct;
38(1):e5275.
PMID: 39468867
Diabetes affects metabolism and metabolite concentrations in multiple organs. Previous preclinical studies have shown that receptor for advanced glycation end products (RAGE, gene symbol Ager) and its cytoplasmic domain binding...
3.
Ramasamy R, Shekhtman A, Schmidt A
Atherosclerosis
. 2024 Aug;
394.
PMID: 39131441
Background And Aims: In hyperglycemia, inflammation, oxidative stress and aging, Damage Associated Molecular Patterns (DAMPs) accumulate in conditions such as atherosclerosis. Binding of DAMPs to receptors such as the receptor...
4.
Yu J, Ramirez L, Lin Q, Burz D, Shekhtman A
J Phys Chem B
. 2024 Jul;
128(29):7002-7021.
PMID: 39012038
Ribosomes bind to many metabolic enzymes and change their activity. A general mechanism for ribosome-mediated amplification of metabolic enzyme activity, RAMBO, was formulated and elucidated for the glycolytic enzyme triosephosphate...
5.
Ramasamy R, Shekhtman A, Schmidt A
Arterioscler Thromb Vasc Biol
. 2024 Jun;
44(7):1497-1501.
PMID: 38924438
No abstract available.
6.
Chen H, Zhang Y, Wen Y, Fan X, Sciolino N, Lin Y, et al.
Nat Commun
. 2024 Jun;
15(1):5372.
PMID: 38918367
The synthesis of constrained 12-membered rings is notably difficult. The main challenges result from constraints during the linear peptide cyclization. Attempts to overcome constraints through excessive activation frequently cause peptidyl...
7.
Almehmadi L, Reverdatto S, Ermolenkov V, Shekhtman A, Lednev I
Anal Chem
. 2023 Dec;
96(3):1003-1008.
PMID: 38052070
Deep-UV resonance Raman spectroscopy has been shown to offer great potential for probing the in situ stability of mRNA vaccines. In this study, a vaccine model was subjected to controlled...
8.
Yepuri G, Ramirez L, Theophall G, Reverdatto S, Quadri N, Hasan S, et al.
Nat Commun
. 2023 Oct;
14(1):6900.
PMID: 37903764
Inter-organelle contact and communication between mitochondria and sarco/endoplasmic reticulum (SR/ER) maintain cellular homeostasis and are profoundly disturbed during tissue ischemia. We tested the hypothesis that the formin Diaphanous-1 (DIAPH1), which...
9.
Theophall G, Ramirez L, Premo A, Reverdatto S, Manigrasso M, Yepuri G, et al.
J Biol Chem
. 2023 Oct;
299(11):105342.
PMID: 37832872
The diaphanous-related formin, Diaphanous 1 (DIAPH1), is required for the assembly of Filamentous (F)-actin structures. DIAPH1 is an intracellular effector of the receptor for advanced glycation end products (RAGE) and...
10.
Wilson R, Arivazhagan L, Ruiz H, Zhou B, Qian K, Manigrasso M, et al.
Obesity (Silver Spring)
. 2023 May;
31(7):1825-1843.
PMID: 37231626
Objective: Optimal body mass and composition as well as metabolic fitness require tightly regulated and interconnected mechanisms across tissues. Disturbances in these regulatory networks tip the balance between metabolic health...