David Redmond
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Explore the profile of David Redmond including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Redmond D, Rafii S
Nat Cell Biol
. 2023 Oct;
25(10):1406-1407.
PMID: 37798544
No abstract available.
12.
Stamateris R, Landa-Galvan H, Sharma R, Darko C, Redmond D, Rane S, et al.
J Clin Invest
. 2023 Sep;
133(18).
PMID: 37712417
Expanding β cell mass is a critical goal in the fight against diabetes. CDK4, an extensively characterized cell cycle activator, is required to establish and maintain β cell number. β...
13.
Elhadad S, Redmond D, Huang J, Tan A, Laurence J
Clin Exp Immunol
. 2023 May;
213(2):252-264.
PMID: 37191586
Transplant-associated thrombotic microangiopathy (TA-TMA) is an endotheliopathy complicating up to 30% of allogeneic hematopoietic stem cell transplants (alloHSCT). Positive feedback loops among complement, pro-inflammatory, pro-apoptotic, and coagulation cascade likely assume...
14.
Moeller T, Shah S, Lai K, Lopez-Barbosa N, Desai P, Wang W, et al.
ACS Cent Sci
. 2023 May;
9(4):787-804.
PMID: 37122450
Glycoengineered bacteria have emerged as a cost-effective platform for rapid and controllable biosynthesis of designer conjugate vaccines. However, little is known about the engagement of such conjugates with naïve B...
15.
Ramalingam P, Gutkin M, Poulos M, Tillery T, Doughty C, Winiarski A, et al.
Nat Commun
. 2023 Apr;
14(1):2018.
PMID: 37037837
Aging associated defects within stem cell-supportive niches contribute towards age-related decline in stem cell activity. However, mechanisms underlying age-related niche defects, and whether restoring niche function can improve stem cell...
16.
Itkin T, Houghton S, Schreiner R, Lin Y, Badwe C, Voisin V, et al.
bioRxiv
. 2023 Apr;
PMID: 37034724
Transition between activation and quiescence programs in hematopoietic stem and progenitor cells (HSC/HSPCs) is perceived to be governed intrinsically and by microenvironmental co-adaptation. However, HSC programs dictating both transition and...
17.
Hirschhorn D, Budhu S, Kraehenbuehl L, Gigoux M, Schroder D, Chow A, et al.
Cell
. 2023 Mar;
186(7):1432-1447.e17.
PMID: 37001503
Cancer immunotherapies, including adoptive T cell transfer, can be ineffective because tumors evolve to display antigen-loss-variant clones. Therapies that activate multiple branches of the immune system may eliminate escape variants....
18.
Elhadad S, Redmond D, Tan A, Huang J, Rodriguez B, Racine-Brzostek S, et al.
Thromb Res
. 2023 Mar;
225:47-56.
PMID: 37001283
Background And Objectives: COVID-19 progression is characterized by systemic small vessel arterial and venous thrombosis. Microvascular endothelial cell (MVEC) activation and injury, platelet activation, and histopathologic features characteristic of acute...
19.
Gaynor K, OReilly M, Redmond D, Nealon C, Twomey C, Hennessy E
Compr Psychiatry
. 2023 Feb;
122:152374.
PMID: 36758338
Introduction: Suicidality among young people is a significant societal issue. The current study conducted a meta-analysis of community and clinical interventions targeting suicide attempts, self-harm, and suicidal ideation in adolescents....
20.
Gomez-Salinero J, Itkin T, Houghton S, Badwe C, Lin Y, Kalna V, et al.
Nat Cardiovasc Res
. 2023 Jan;
1:882-899.
PMID: 36713285
Current dogma dictates that during adulthood, endothelial cells (ECs) are locked in an immutable stable homeostatic state. By contrast, herein we show that maintenance of EC fate and function are...