Sean Houghton
Overview
Explore the profile of Sean Houghton including associated specialties, affiliations and a list of published articles.
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25
Citations
1165
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Recent Articles
1.
Itkin T, Houghton S, Schreiner R, Lin Y, Badwe C, Voisin V, et al.
Nat Immunol
. 2025 Feb;
26(3):378-390.
PMID: 40000903
Transition between activation and quiescence states in hematopoietic stem and progenitor cells (HSPCs) is tightly governed by cell-intrinsic means and microenvironmental co-adaptation. Although this balance is fundamental for lifelong hematopoiesis...
2.
Summers B, Kim K, Trivedi A, Lu T, Houghton S, Palmer-Johnson J, et al.
Am J Physiol Lung Cell Mol Physiol
. 2024 Oct;
328(1):L1-L14.
PMID: 39437762
We have previously shown that mice with a loss of C-type lectin-like type II (CLEC2), which have lymphatic dysfunction due to the role of CLEC2 in platelets for maintaining separation...
3.
Ranti D, Yu H, Wang Y, Bieber C, Strandgaard T, Salome B, et al.
bioRxiv
. 2024 Sep;
PMID: 39282294
Bacillus Calmette-Guerin (BCG) is the primary treatment for non-muscle-invasive bladder cancer (NMIBC), known to stimulate inflammatory cytokines, notably interferon (IFN)-γ. We observed that prolonged IFN-γ exposure fosters adaptive resistance in...
4.
Venkatraman S, Gomez Salinero J, Scheinfeld A, Houghton S, Redmond D, Safford M, et al.
BMC Public Health
. 2024 Jul;
24(1):1994.
PMID: 39061026
Background: Recent studies have demonstrated that individuals hospitalized due to COVID-19 can be affected by "long-COVID" symptoms for as long as one year after discharge. Objectives: Our study objective is...
5.
Han Y, Duan X, Yang L, Nilsson-Payant B, Wang P, Duan F, et al.
Nature
. 2024 May;
630(8016):E7.
PMID: 38811742
No abstract available.
6.
Trivedi A, Lu T, Summers B, Kim K, Rhee A, Houghton S, et al.
Front Cell Dev Biol
. 2024 Mar;
12:1344070.
PMID: 38440076
The lymphatic vasculature regulates lung homeostasis through drainage of fluid and trafficking of immune cells and plays a key role in the response to lung injury in several disease states....
7.
Summers B, Kim K, Lu T, Houghton S, Trivedi A, Quintero J, et al.
bioRxiv
. 2023 Nov;
PMID: 37961242
Chronic Obstructive Pulmonary Disease (COPD) is a heterogeneous disease that is characterized by many clinical phenotypes. One such phenotype of COPD is defined by emphysema, pathogenic lung tertiary lymphoid organs...
8.
Itkin T, Houghton S, Schreiner R, Lin Y, Badwe C, Voisin V, et al.
bioRxiv
. 2023 Apr;
PMID: 37034724
Transition between activation and quiescence programs in hematopoietic stem and progenitor cells (HSC/HSPCs) is perceived to be governed intrinsically and by microenvironmental co-adaptation. However, HSC programs dictating both transition and...
9.
Gomez-Salinero J, Itkin T, Houghton S, Badwe C, Lin Y, Kalna V, et al.
Nat Cardiovasc Res
. 2023 Jan;
1:882-899.
PMID: 36713285
Current dogma dictates that during adulthood, endothelial cells (ECs) are locked in an immutable stable homeostatic state. By contrast, herein we show that maintenance of EC fate and function are...
10.
Argueta L, Lacko L, Bram Y, Tada T, Carrau L, Rendeiro A, et al.
iScience
. 2022 Apr;
25(5):104223.
PMID: 35434541
The effect of SARS-CoV-2 infection on placental function is not well understood. Analysis of placentas from women who tested positive at delivery showed SARS-CoV-2 genomic and subgenomic RNA in 22...