David Ramonet
Overview
Explore the profile of David Ramonet including associated specialties, affiliations and a list of published articles.
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15
Citations
712
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0
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Recent Articles
1.
Beccari S, Sierra-Torre V, Valero J, Pereira-Iglesias M, Garcia-Zaballa M, Soria F, et al.
Autophagy
. 2023 Jan;
19(7):1952-1981.
PMID: 36622892
Microglial phagocytosis of apoptotic debris prevents buildup damage of neighbor neurons and inflammatory responses. Whereas microglia are very competent phagocytes under physiological conditions, we report their dysfunction in mouse and...
2.
Debatisse J, Eker O, Wateau O, Cho T, Wiart M, Ramonet D, et al.
Brain Commun
. 2020 Dec;
2(2):fcaa193.
PMID: 33305265
In an acute ischaemic stroke, understanding the dynamics of blood-brain barrier injury is of particular importance for the prevention of symptomatic haemorrhagic transformation. However, the available techniques assessing blood-brain barrier...
3.
Ramonet D, Dietz G
SLAS Discov
. 2019 Aug;
25(1):104-112.
PMID: 31373835
Mutations in the gene encoding leucine-rich repeat kinase 2 (), such as the G2019S mutation, are the most common cause of familial Parkinson's disease (PD). The G2019S mutation impairs neurite...
4.
Ramirez A, van der Flier W, Herold C, Ramonet D, Heilmann S, Lewczuk P, et al.
Hum Mol Genet
. 2014 Jul;
23(24):6644-58.
PMID: 25027320
Cerebrospinal fluid amyloid-beta 1-42 (Aβ1-42) and phosphorylated Tau at position 181 (pTau181) are biomarkers of Alzheimer's disease (AD). We performed an analysis and meta-analysis of genome-wide association study data on...
5.
Gockel I, Becker J, Wouters M, Niebisch S, Gockel H, Hess T, et al.
Nat Genet
. 2014 Jul;
46(8):901-4.
PMID: 24997987
Idiopathic achalasia is characterized by a failure of the lower esophageal sphincter to relax due to a loss of neurons in the myenteric plexus. This ultimately leads to massive dilatation...
6.
Ramonet D, Podhajska A, Stafa K, Sonnay S, Trancikova A, Tsika E, et al.
Hum Mol Genet
. 2011 Dec;
21(8):1725-43.
PMID: 22186024
Mutations in the ATP13A2 gene (PARK9, OMIM 610513) cause autosomal recessive, juvenile-onset Kufor-Rakeb syndrome and early-onset parkinsonism. ATP13A2 is an uncharacterized protein belonging to the P(5)-type ATPase subfamily that is...
7.
Buscemi L, Ramonet D, Klingberg F, Formey A, Smith-Clerc J, Meister J, et al.
Curr Biol
. 2011 Dec;
21(24):2046-54.
PMID: 22169532
Background: TGF-β1 controls many pathophysiological processes including tissue homeostasis, fibrosis, and cancer progression. Together with its latency-associated peptide (LAP), TGF-β1 binds to the latent TGF-β1-binding protein-1 (LTBP-1), which is part...
8.
Ramonet D, Daher J, Lin B, Stafa K, Kim J, Banerjee R, et al.
PLoS One
. 2011 Apr;
6(4):e18568.
PMID: 21494637
Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene cause late-onset, autosomal dominant familial Parkinson's disease (PD) and also contribute to idiopathic PD. LRRK2 mutations represent the most common cause...
9.
Trancikova A, Ramonet D, Moore D
Prog Mol Biol Transl Sci
. 2011 Mar;
100:419-82.
PMID: 21377633
Neurodegenerative diseases are generally characterized by the selective degeneration of particular neuronal populations and the accumulation of abnormal or aggregated proteins within, but occasionally external to, neurons in affected brain...
10.
Deng P, Xiao Z, Jha A, Ramonet D, Matsui T, Leitges M, et al.
J Neurosci
. 2010 Apr;
30(15):5136-48.
PMID: 20392936
Cholecystokinin (CCK), a neuropeptide originally discovered in the gastrointestinal tract, is abundantly distributed in the mammalian brains including the hippocampus. Whereas CCK has been shown to increase glutamate concentration in...