David R Shaffer
Overview
Explore the profile of David R Shaffer including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
1708
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Recent Articles
11.
Shaffer D, Leversha M, Danila D, Lin O, Gonzalez-Espinoza R, Gu B, et al.
Clin Cancer Res
. 2007 Apr;
13(7):2023-9.
PMID: 17404082
Purpose: To better direct targeted therapies to the patients with tumors that express the target, there is an urgent need for blood-based assays that provide expression information on a consistent...
12.
13.
Villanueva J, Shaffer D, Philip J, Chaparro C, Erdjument-Bromage H, Olshen A, et al.
J Clin Invest
. 2006 Jan;
116(1):271-84.
PMID: 16395409
Recent studies have established distinctive serum polypeptide patterns through mass spectrometry (MS) that reportedly correlate with clinically relevant outcomes. Wider acceptance of these signatures as valid biomarkers for disease may...
14.
Peduto L, Reuter V, Shaffer D, Scher H, Blobel C
Cancer Res
. 2005 Oct;
65(20):9312-9.
PMID: 16230393
ADAM9 is a membrane-anchored metalloprotease that is markedly up-regulated in several human carcinomas. Here, we show that ADAM9 is similarly up-regulated in mouse models for prostate, breast, and intestinal carcinoma....
15.
Shaffer D, Viale A, Ishiwata R, Leversha M, Olgac S, Manova K, et al.
Proc Natl Acad Sci U S A
. 2004 Dec;
102(1):210-5.
PMID: 15615849
Reduced p27 levels correlate with poor prognosis in a wide spectrum of human tumors and can accelerate tumorigenesis in mouse tissues. To determine whether p27 deficiency can accelerate tumorigenesis in...
16.
Shaffer D, Scher H
Lancet Oncol
. 2003 Jul;
4(7):407-14.
PMID: 12850191
Despite high response rates and palliative clinical benefits, androgen ablation does not cure advanced prostate cancer because of the inevitable emergence of resistant cells. Many new therapies under development for...
17.
Williamson G, Walters A, Shaffer D
Health Psychol
. 2002 Jul;
21(4):405-10.
PMID: 12090684
In a sample of 59 chronically ill pediatric patients and their maternal caregivers, both child-reported pain and caregiver-reported depression predicted child-reported depression. Results further suggested that the association between pain...