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David Quartermain

Explore the profile of David Quartermain including associated specialties, affiliations and a list of published articles. Areas
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Articles 43
Citations 1213
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Recent Articles
11.
Haile M, Limson F, Gingrich K, Li Y, Quartermain D, Blanck T, et al.
J Neurosurg Anesthesiol . 2009 Mar; 21(2):140-4. PMID: 19295393
Background: Cognitive changes associated with moderate hypoxia may be related to the elevation of cytosolic calcium (Ca) levels which may, in turn, affect neurotransmitter synthesis and metabolism. We tested whether...
12.
Li Z, Nardi M, Li Y, Zhang W, Pan R, Dang S, et al.
Blood . 2009 Feb; 113(24):6051-60. PMID: 19218546
Anti-platelet integrin GPIIIa49-66 antibody (Ab) induces complement-independent platelet oxidative fragmentation and death by generation of platelet peroxide following NADPH oxidase activation. A C-terminal 385-amino acid fragment of ADAMTS-18 (a disintegrin...
13.
Stone E, Lin Y, Quartermain D
Pharmacol Biochem Behav . 2008 Aug; 91(1):190-5. PMID: 18692087
The present study evaluated the extension of a new rat model of depression, repeated open-space swimming, which overcomes drawbacks of existing models, to mice. Mice were swum for 15 min...
14.
Scholtzova H, Wadghiri Y, Douadi M, Sigurdsson E, Li Y, Quartermain D, et al.
J Neurosci Res . 2008 Jul; 86(12):2784-91. PMID: 18615702
Memantine, an N-methyl-D-aspartate (NMDA) receptor antagonist, has been shown to improve learning and memory in several preclinical models of Alzheimer's disease (AD). Memantine has also been shown to reduce the...
15.
Lin Y, Quartermain D, Dunn A, Weinshenker D, Stone E
Synapse . 2008 Apr; 62(7):516-23. PMID: 18435418
alpha(1)-Adrenoceptors of the locus coeruleus (LC) have been implicated in behavioral activation in novel surroundings, but the endogenous agonist that activates these receptors has not been established. In addition to...
16.
Stone E, Lin Y, Quartermain D
Neurosci Biobehav Rev . 2007 Nov; 32(3):508-24. PMID: 18023876
Functional neuroimaging studies of depressed patients have converged with functional brain mapping studies of depressed animals in showing that depression is accompanied by a hypoactivity of brain regions involved in...
17.
Bekker A, Haile M, Gingrich K, Wenning L, Gorny A, Quartermain D, et al.
Anesth Analg . 2007 Aug; 105(3):739-43. PMID: 17717233
Background: Cognitive changes associated with moderate hypoxia in rodents may result from the diminished functioning of central cholinergic neurotransmission. We designed this study to examine whether treatment with physostigmine (PHY),...
18.
Asuni A, Boutajangout A, Quartermain D, Sigurdsson E
J Neurosci . 2007 Aug; 27(34):9115-29. PMID: 17715348
Immunotherapies for various neurodegenerative diseases have recently emerged as a promising approach for clearing pathological protein conformers in these disorders. This type of treatment has not been assessed in models...
19.
Quartermain D, Li Y, Jonas S
Neurol Res . 2007 May; 29(5):469-75. PMID: 17535591
Objectives: The purpose of this experiment was to determine if the low molecular weight heparin (LMWH) enoxaparin could extend the treatment window for thrombolysis in a mouse model of embolic...
20.
Stone E, Lehmann M, Lin Y, Quartermain D
Prog Neuropsychopharmacol Biol Psychiatry . 2007 May; 31(6):1196-207. PMID: 17513031
A previous study showed that two mouse models of behavioral depression, immune system activation and depletion of brain monoamines, are accompanied by marked reductions in stimulated neural activity in brain...