David P Sullivan
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Explore the profile of David P Sullivan including associated specialties, affiliations and a list of published articles.
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33
Citations
679
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Recent Articles
1.
Li J, Shih L, Markwell S, Olson C, Sullivan D, Arvanitis C, et al.
Proc Natl Acad Sci U S A
. 2025 Feb;
122(7):e2416024122.
PMID: 39946540
All glioblastoma (GBM) molecular subsets share the common trait of accelerated progression following necrosis, which cannot be adequately explained by cellular proliferation arising from accumulated genetic alterations. Counter to dogma...
2.
DeBerge M, Glinton K, Lantz C, Ge Z, Sullivan D, Patil S, et al.
Nat Cardiovasc Res
. 2025 Jan;
4(1):83-101.
PMID: 39747455
Myocardial infarction (MI) mobilizes macrophages, the central protagonists of tissue repair in the infarcted heart. Although necessary for repair, macrophages also contribute to adverse remodeling and progression to heart failure....
3.
Piccolo E, Ge Z, Filipp M, Sullivan D, Thorp E, Sumagin R
Am J Physiol Heart Circ Physiol
. 2024 Sep;
327(5):H1230-H1243.
PMID: 39331023
Heart failure is a major cause of mortality following myocardial infarction. Neutrophils are among the first immune cells to accumulate in the infarcted region. Although beneficial functions of neutrophils in...
4.
Bui T, Yalom L, Ning E, Urbanczyk J, Ren X, Herrnreiter C, et al.
J Clin Invest
. 2024 Feb;
134(7).
PMID: 38329810
Neutrophil (PMN) tissue accumulation is an established feature of ulcerative colitis (UC) lesions and colorectal cancer (CRC). To assess the PMN phenotypic and functional diversification during the transition from inflammatory...
5.
Haynes M, Sullivan D, Muller W
Am J Pathol
. 2024 Feb;
194(5):628-636.
PMID: 38309429
Neutrophils are an important cell type often considered the body's first responders to inflammatory insult or damage. They are recruited to the tissue of the lungs in patients with inflammatory...
6.
Romay M, Knutsen R, Ma F, Mompeon A, Hernandez G, Salvador J, et al.
J Clin Invest
. 2023 Nov;
134(2).
PMID: 38015629
Vascular aging affects multiple organ systems, including the brain, where it can lead to vascular dementia. However, a concrete understanding of how aging specifically affects the brain vasculature, along with...
7.
Fu T, Sullivan D, Gonzalez A, Haynes M, Dalal P, Rutledge N, et al.
Immunity
. 2023 Aug;
56(10):2311-2324.e6.
PMID: 37643615
Engagement of platelet endothelial cell adhesion molecule 1 (PECAM, PECAM-1, CD31) on the leukocyte pseudopod with PECAM at the endothelial cell border initiates transendothelial migration (TEM, diapedesis). We show, using...
8.
Ren X, Manzanares L, Piccolo E, Urbanczyk J, Sullivan D, Yalom L, et al.
J Clin Invest
. 2023 Jun;
133(15).
PMID: 37261911
Neutrophil (PMN) mobilization to sites of insult is critical for host defense and requires transendothelial migration (TEM). TEM involves several well-studied sequential adhesive interactions with vascular endothelial cells (ECs); however,...
9.
Fang V, Haynes M, Hayashi V, Arias E, Lavine J, Sullivan D, et al.
Curr Protoc
. 2023 Apr;
3(4):e739.
PMID: 37078364
Inflammation is the body's response to injury and harmful stimuli and contributes to a range of infectious and noninfectious diseases. Inflammation occurs through a series of well-defined leukocyte-endothelial cell interactions,...
10.
Nadkarni N, Arias E, Fang R, Haynes M, Zhang H, Muller W, et al.
Am J Pathol
. 2022 Aug;
192(11):1619-1632.
PMID: 35952762
The infiltration of polymorphonuclear leukocytes (PMNs) in ischemia-reperfusion injury (I/RI) has been implicated as a critical component of inflammatory damage following ischemic stroke. However, successful blockade of PMN transendothelial migration...