David Osumi-Sutherland
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Explore the profile of David Osumi-Sutherland including associated specialties, affiliations and a list of published articles.
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Recent Articles
21.
Li H, Janssens J, De Waegeneer M, Kolluru S, Davie K, Gardeux V, et al.
Science
. 2022 Mar;
375(6584):eabk2432.
PMID: 35239393
For more than 100 years, the fruit fly has been one of the most studied model organisms. Here, we present a single-cell atlas of the adult fly, Tabula , that...
22.
Moreno P, Fexova S, George N, Manning J, Miao Z, Mohammed S, et al.
Nucleic Acids Res
. 2021 Dec;
50(D1):D129-D140.
PMID: 34850121
The EMBL-EBI Expression Atlas is an added value knowledge base that enables researchers to answer the question of where (tissue, organism part, developmental stage, cell type) and under which conditions...
23.
Borner K, Teichmann S, Quardokus E, Gee J, Browne K, Osumi-Sutherland D, et al.
Nat Cell Biol
. 2021 Nov;
23(11):1117-1128.
PMID: 34750582
The Human Reference Atlas (HRA) aims to map all of the cells of the human body to advance biomedical research and clinical practice. This Perspective presents collaborative work by members...
24.
Osumi-Sutherland D, Xu C, Keays M, Levine A, Kharchenko P, Regev A, et al.
Nat Cell Biol
. 2021 Nov;
23(11):1129-1135.
PMID: 34750578
Massive single-cell profiling efforts have accelerated our discovery of the cellular composition of the human body while at the same time raising the need to formalize this new knowledge. Here,...
25.
Jackson R, Matentzoglu N, Overton J, Vita R, Balhoff J, Buttigieg P, et al.
Database (Oxford)
. 2021 Oct;
2021.
PMID: 34697637
Biological ontologies are used to organize, curate and interpret the vast quantities of data arising from biological experiments. While this works well when using a single ontology, integrating multiple ontologies...
26.
Shefchek K, Harris N, Gargano M, Matentzoglu N, Unni D, Brush M, et al.
Nucleic Acids Res
. 2019 Nov;
48(D1):D704-D715.
PMID: 31701156
In biology and biomedicine, relating phenotypic outcomes with genetic variation and environmental factors remains a challenge: patient phenotypes may not match known diseases, candidate variants may be in genes that...
27.
Thomas P, Hill D, Mi H, Osumi-Sutherland D, Van Auken K, Carbon S, et al.
Nat Genet
. 2019 Sep;
51(10):1429-1433.
PMID: 31548717
No abstract available.
28.
Koopmans F, van Nierop P, Andres-Alonso M, Byrnes A, Cijsouw T, Coba M, et al.
Neuron
. 2019 Jun;
103(2):217-234.e4.
PMID: 31171447
Synapses are fundamental information-processing units of the brain, and synaptic dysregulation is central to many brain disorders ("synaptopathies"). However, systematic annotation of synaptic genes and ontology of synaptic processes are...
29.
Kohler S, Carmody L, Vasilevsky N, Jacobsen J, Danis D, Gourdine J, et al.
Nucleic Acids Res
. 2018 Nov;
47(D1):D1018-D1027.
PMID: 30476213
The Human Phenotype Ontology (HPO)-a standardized vocabulary of phenotypic abnormalities associated with 7000+ diseases-is used by thousands of researchers, clinicians, informaticians and electronic health record systems around the world. Its...
30.
Osumi-Sutherland D, Costa M, Court R, OKane C
CEUR Workshop Proc
. 2018 May;
1265:85-96.
PMID: 29724079
A massive effort is underway to map the structure of the nervous system and to genetically dissect its function. Virtual Fly Brain (VFB; http://www.virtualflybrain.org) is a popular, OWL-based resource providing...