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David Nochlin

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Articles 17
Citations 571
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Recent Articles
11.
Wijsman E, Daw E, Yu X, Steinbart E, Nochlin D, Bird T, et al.
Am J Med Genet B Neuropsychiatr Genet . 2004 Sep; 132B(1):14-20. PMID: 15389756
Several kindreds of Volga German (VG) ancestry have a single PS2 mutation that causes an autosomal dominant form of Alzheimer's disease (AD). These families show a wide range in age-at-onset,...
12.
Riekse R, Leverenz J, McCormick W, Bowen J, Teri L, Nochlin D, et al.
J Am Geriatr Soc . 2004 Sep; 52(9):1442-8. PMID: 15341544
Objectives: To investigate whether clinical and neuropathological differences exist between Alzheimer's disease (AD) cases with and without vascular lesions neuropathologically diagnosed using Consortium to Establish a Registry for Alzheimer's Disease...
13.
Wijsman E, Daw E, Yu C, Payami H, Steinbart E, Nochlin D, et al.
Am J Hum Genet . 2004 Jul; 75(3):398-409. PMID: 15248153
Late-onset familial Alzheimer disease (LOFAD) is a genetically heterogeneous and complex disease for which only one locus, APOE, has been definitively identified. Difficulties in identifying additional loci are likely to...
14.
Chen D, Brkanac Z, Verlinde C, Tan X, Bylenok L, Nochlin D, et al.
Am J Hum Genet . 2003 Mar; 72(4):839-49. PMID: 12644968
We report a nonepisodic autosomal dominant (AD) spinocerebellar ataxia (SCA) not caused by a nucleotide repeat expansion that is, to our knowledge, the first such SCA. The AD SCAs currently...
15.
Tomashevski A, Husseman J, Jin L, Nochlin D, Vincent I
J Alzheimers Dis . 2002 Sep; 3(2):195-207. PMID: 12214061
The cdc2/cyclin B1 kinase is absent from neurons that are terminally differentiated. However, unscheduled activation of Cdc2/cyclin B and accumulation of mitotic phosphoepitopes have been described in degenerating neurons of...
16.
Brkanac Z, Bylenok L, Fernandez M, Matsushita M, Lipe H, Wolff J, et al.
Arch Neurol . 2002 Aug; 59(8):1291-5. PMID: 12164726
Background: The autosomal dominant spinocerebellar ataxias (SCAs) are a clinically and genetically heterogeneous group of neurodegenerative disorders. Although molecular genetic studies have so far implicated 16 loci in the etiology...
17.
Leverenz J, Agustin C, Tsuang D, Peskind E, Edland S, Nochlin D, et al.
Arch Neurol . 2002 Jul; 59(7):1099-106. PMID: 12117357
Background: Hippocampal sclerosis (HS) is a neuropathologic finding characterized by neuronal loss and gliosis in the CA-1 and subiculum of the hippocampus. Previous studies of HS have shown that this...