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Steven D Edland

Explore the profile of Steven D Edland including associated specialties, affiliations and a list of published articles. Areas
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Articles 94
Citations 2072
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Recent Articles
1.
Coughlin D, Shifflett B, Farris C, Ma Y, Galasko D, Edland S, et al.
Neurology . 2025 Feb; 104(5):e210279. PMID: 39913882
Objectives: Tools are needed to evaluate the risk of developing Parkinson disease (PD) in at-risk populations. In this study, we examine differences in alpha-synuclein seed amplification assay (αSyn-SAA) qualitative results...
2.
Wang X, Wang X, Edland S, Broce I, Dale A, Banks S
Alzheimers Dement . 2024 Oct; 20(12):8484-8502. PMID: 39440707
Introduction: Identifying low-cost, minimally-invasive screening instruments for Alzheimer's disease (AD) trial enrichment will improve the efficiency of AD trials. Methods: A total of 685 cognitively normal (CN) individuals and individuals...
3.
Xia J, Kutas M, Salmon D, Stoermann A, Rigatuso S, Tomaszewski Farias S, et al.
Cereb Cortex . 2024 Oct; 34(10). PMID: 39390709
Impaired episodic memory is the primary feature of early Alzheimer's disease (AD), but not all memories are equally affected. Patients with AD and amnestic Mild Cognitive Impairment (aMCI) remember pictures...
4.
Bernier R, Sundermann E, Edland S, Deters K, Shepherd A, Clark A, et al.
J Appl Gerontol . 2024 Jun; 43(12):1939-1949. PMID: 38835249
High-density lipoprotein (HDL) is protective against cardiovascular disease. Exercise can increase HDL concentration, and some evidence suggests that this effect occurs more strongly in women than in men. Both HDL...
5.
Feldman H, Luchsinger J, Leger G, Taylor C, Jacobs D, Salmon D, et al.
PLoS One . 2024 May; 19(5):e0302998. PMID: 38809849
Background: Benfotiamine provides an important novel therapeutic direction in Alzheimer's disease (AD) with possible additive or synergistic effects to amyloid targeting therapeutic approaches. Objective: To conduct a seamless phase 2A-2B...
6.
Wang X, Jacobs D, Salmon D, Feldman H, Edland S
Int J Stat Med Res . 2024 Mar; 12:90-96. PMID: 38487620
Introduction: Cognitive composite scales constructed by combining existing neuropsychometric tests are seeing wide application as endpoints for clinical trials and cohort studies of Alzheimer's disease (AD) predementia conditions. Preclinical Alzheimer's...
7.
Edland S, Llibre-Guerra J
Neurology . 2023 Aug; 101(14):593-594. PMID: 37643886
No abstract available.
8.
Wang X, Broce I, Qiu Y, Deters K, Fan C, Dale A, et al.
Alzheimers Dement . 2023 Jan; 19(7):3078-3086. PMID: 36701211
Introduction: Identifying individuals who are most likely to accumulate tau and exhibit cognitive decline is critical for Alzheimer's disease (AD) clinical trials. Methods: Participants (N = 235) who were cognitively...
9.
Tsiknia A, Sundermann E, Reas E, Edland S, Brewer J, Galasko D, et al.
Alzheimers Res Ther . 2022 Nov; 14(1):160. PMID: 36324151
Background: Studies have reported higher plasma matrix metalloproteinase-9 (MMP-9) levels in mild cognitive impairment (MCI) and Alzheimer's disease (AD). Despite evidence that MMP-9 activity and its influence on AD pathophysiology...
10.
Tsiknia A, Edland S, Sundermann E, Reas E, Brewer J, Galasko D, et al.
Mol Psychiatry . 2022 Jun; 27(10):4314-4322. PMID: 35768637
Studies have shown that women on the Alzheimer's disease (AD) continuum have more pathological tau in the brain and cerebrospinal fluid (CSF), than men. Some studies have found that higher...