David N Harrison
Overview
Explore the profile of David N Harrison including associated specialties, affiliations and a list of published articles.
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5
Citations
66
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Recent Articles
1.
Narasimhulu V, Bellamy-McIntyre A, Laumaea A, Lay C, Harrison D, King H, et al.
J Biol Chem
. 2018 Mar;
293(16):6099-6120.
PMID: 29496992
HIV-1 is spread by cell-free virions and by cell-cell viral transfer. We asked whether the structure and function of a broad neutralizing antibody (bNAb) epitope, the membrane-proximal ectodomain region (MPER)...
2.
Khasawneh A, Laumaea A, Harrison D, Bellamy-McIntyre A, Drummer H, Poumbourios P
Retrovirology
. 2013 Apr;
10:44.
PMID: 23618462
Background: The disulfide-bonded region (DSR) of HIV-1 gp41 mediates association with gp120 and plays a role in transmission of receptor-induced conformational changes in gp120 to gp41 that activate membrane fusion...
3.
Gazina E, Smidansky E, Holien J, Harrison D, Cromer B, Arnold J, et al.
J Virol
. 2011 Jul;
85(19):10364-74.
PMID: 21795353
Amiloride and its derivative 5-(N-ethyl-N-isopropyl)amiloride (EIPA) were previously shown to inhibit coxsackievirus B3 (CVB3) RNA replication in cell culture, with two amino acid substitutions in the viral RNA-dependent RNA polymerase...
4.
Harrison D, Gazina E, Purcell D, Anderson D, Petrou S
J Virol
. 2007 Nov;
82(3):1465-73.
PMID: 18032495
Amiloride derivatives are known blockers of the cellular Na(+)/H(+) exchanger and the epithelial Na(+) channel. More recent studies demonstrate that they also inhibit ion channels formed by a number of...
5.
Gazina E, Harrison D, Jefferies M, Tan H, Williams D, Anderson D, et al.
Antiviral Res
. 2005 Aug;
67(2):98-106.
PMID: 16054245
Picornavirus replication causes leakage of cytoplasmic K+ and an influx of Na+ and Ca2+. In this study, we have explored the possibility that a blockade of Ca2+ and Na+ influx...