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David N Criddle

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Articles 62
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Recent Articles
1.
Chvanov M, Voronina S, Jefferson M, Mayer U, Sutton R, Criddle D, et al.
Autophagy . 2024 Aug; 21(1):210-222. PMID: 39216469
The WD40 domain (WDD) of ATG16L1 plays a pivotal role in non-canonical autophagy. This study examined the role of recently identified LAP-like non-canonical autophagy (LNCA) in acute pancreatitis. LNCA involves...
2.
Criddle D, Tepikin A
Cell Calcium . 2024 Mar; 119:102868. PMID: 38457907
The recent elegant study by Y. Yuan and colleagues examined functional relationships between the lysosomal two-pore channels 2 (TPC2) and IP3 receptors (IP3Rs) located in the endoplasmic reticulum [1]. The...
3.
Vallabh N, Armstrong J, Czanner G, McDonagh B, Choudhary A, Criddle D, et al.
Free Radic Biol Med . 2022 Jul; 189:102-110. PMID: 35872337
Glaucoma is a progressive optic neuropathy characterized by the neurodegeneration of the retinal ganglion cells (RGCs) resulting in irreversible visual impairment and eventual blindness. RGCs are extremely susceptible to mitochondrial...
4.
Yang X, Yao L, Yuan M, Zhang X, Jakubowska M, Ferdek P, et al.
Front Pharmacol . 2022 Jun; 13:896523. PMID: 35754467
Obesity-related acute pancreatitis (AP) is characterized by increasing prevalence worldwide and worse clinical outcomes compared to AP of other etiologies. Chaiqin chengqi decoction (CQCQD), a Chinese herbal formula, has long...
5.
Du W, Liu G, Shi N, Tang D, Ferdek P, Jakubowska M, et al.
Mol Ther . 2022 Jan; 30(4):1754-1774. PMID: 35077860
Acute pancreatitis (AP) is a common digestive disease without specific treatment, and its pathogenesis features multiple deleterious amplification loops dependent on translation, triggered by cytosolic Ca ([Ca]) overload; however, the...
6.
Criddle D, Tepikin A
Cell Calcium . 2021 Sep; 99:102471. PMID: 34517215
Salivary secretion is important for digestion and paramount for oral health. Both exocytotic secretion of proteins (including salivary amylase and mucins) and fluid secretion contribute to the formation of saliva....
7.
Ouyang Y, Wen L, Armstrong J, Chvanov M, Latawiec D, Cai W, et al.
Cells . 2021 Apr; 10(5). PMID: 33925729
Acute pancreatitis (AP) is a severe and potentially fatal disease caused predominantly by alcohol excess and gallstones, which lacks a specific therapy. The role of Receptor-Interacting Protein Kinase 1 (RIPK1),...
8.
Armstrong J, Sutton R, Criddle D
Bio Protoc . 2021 Mar; 10(10):e3627. PMID: 33659300
Mitochondrial dysfunction is a principal feature of acute pancreatitis (AP) although the underlying mechanisms are still unclear. AP precipitants induce Ca-dependent formation of the mitochondrial permeability transition pore (MPTP) in...
9.
Chvanov M, Voronina S, Zhang X, Telnova S, Chard R, Ouyang Y, et al.
Cells . 2020 Jun; 9(6). PMID: 32516955
Acute pancreatitis is a frequent disease that lacks specific drug treatment. Unravelling the molecular mechanisms of acute pancreatitis is essential for the development of new therapeutics. Several inducers of acute...
10.
Ma X, Jin T, Han C, Shi N, Liang G, Wen Y, et al.
J Ethnopharmacol . 2020 Apr; 257:112861. PMID: 32315735
Ethnopharmacological Relevance: Dachengqi decoction (DCQD) belongs to a family of purgative herbal formulas widely used in China for the treatment of acute pancreatitis (AP). AP is a prevalent digestive disease...