David Mu
Overview
Explore the profile of David Mu including associated specialties, affiliations and a list of published articles.
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39
Citations
4214
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Recent Articles
1.
Kong Y, Edler M, Hamel E, Britton-Jenkins A, Gillan O, Mooberry S, et al.
Bioorg Med Chem
. 2024 Nov;
116:117999.
PMID: 39546933
The boronic acid group plays an important role in drug discovery. Following our discovery of a boronic acid analog of combretastatin A-4 (CA-4), a series of analogs featuring a boronic...
2.
Kumar V, Kong Y, Dolland R, Brown S, Wang K, Dolland D, et al.
Antioxidants (Basel)
. 2024 Oct;
13(10).
PMID: 39456460
Radiation-induced cataracts (RICs) represent a significant public health challenge, particularly impacting individuals exposed to ionizing radiation (IR) through medical treatments, occupational settings, and environmental factors. Effective therapeutic strategies require a...
3.
Boothe P, Kumar V, Kong Y, Wang K, Levinson H, Mu D, et al.
Int J Mol Sci
. 2024 Aug;
25(15).
PMID: 39125831
Medical procedures, such as radiation therapy, are a vital element in treating many cancers, significantly contributing to improved survival rates. However, a common long-term complication of such exposure is radiation-induced...
4.
Bard J, Yeluru H, Karpov M, Mu D
Cureus
. 2023 Sep;
15(8):e43067.
PMID: 37680401
Introduction The United States Medical Licensing Examination Step 1 change to Pass/Fail scoring has motivated medical students to pursue more research opportunities. To support students, a student-led organization was created...
5.
Martin S, Mu D
MicroPubl Biol
. 2022 Nov;
2022.
PMID: 36447529
Gap Junction intercellular communication (GJIC) is often dysregulated in cancers, and this dysregulation has been shown to have pro-tumorigenic effects. Connexins (Cxs) are transmembrane proteins that make up gap junctions....
6.
Fleck A, Flotte A, Si E, Mu D
MicroPubl Biol
. 2022 Nov;
2022.
PMID: 36447528
Gap junctions (GJs) and small extracellular vesicles such as exosomes are two fundamental intercellular communication (IC) mechanisms. We tested the hypothesis that the two IC mechanisms are connected by gene...
7.
Maslyanko M, Harris R, Mu D
Int J Mol Sci
. 2021 Jul;
22(13).
PMID: 34281263
Cholesterol is a foundational molecule of biology. There is a long-standing interest in understanding how cholesterol metabolism is intertwined with cancer biology. In this review, we focus on the known...
8.
Phelps C, Lindsey-Boltz L, Sancar A, Mu D
Sci Rep
. 2019 May;
9(1):7990.
PMID: 31142791
The lung lineage master regulator gene, Thyroid Transcription Factor-1 (TTF-1, also known as NKX2-1), is used as a marker by pathologists to identify lung adenocarcinomas since TTF-1 is expressed in...
9.
Lai S, Phelps C, Short A, Dutta S, Mu D
Oncogene
. 2018 Mar;
37(24):3290-3300.
PMID: 29551766
We have discovered an unexpected connection between a critical lung development and cancer gene termed thyroid transcription factor 1 (TTF-1 also known as NKX2-1) and cholesterol metabolism. Our published work...
10.
Phelps C, Lai S, Mu D
Vitam Horm
. 2018 Feb;
106:517-544.
PMID: 29407447
Thyroid transcription factor 1 (TTF-1 or NKX2-1) is a transcription factor of fundamental importance in driving lung maturation and morphogenesis. In the last decade, scientists began to appreciate the functional...