David M Roth
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Explore the profile of David M Roth including associated specialties, affiliations and a list of published articles.
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108
Citations
3151
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Recent Articles
1.
Chitteti R, Zuniga-Hertz J, Zuniga Hertz J, Masso-Silva J, Shin J, Niesman I, et al.
Free Radic Biol Med
. 2025 Jan;
228:329-338.
PMID: 39756490
Inhaling aerosols from electronic nicotine delivery systems, such as e-cigarettes (e-cigs), may pose health risks beyond those caused by nicotine intake. Exposure to e-cig aerosols can lead to the release...
2.
Tchoe Y, Wu T, U H, Roth D, Kim D, Lee J, et al.
Sci Transl Med
. 2024 Apr;
16(744):eadj7257.
PMID: 38657026
Functional mapping during brain surgery is applied to define brain areas that control critical functions and cannot be removed. Currently, these procedures rely on verbal interactions between the neurosurgeon and...
3.
Kopp E, Deussen D, Cuomo R, Lorenz R, Roth D, Mahata S, et al.
Cells
. 2023 Dec;
12(24.
PMID: 38132105
Type 2 diabetes (T2D) has a complex pathophysiology which makes modeling the disease difficult. We aimed to develop a novel model for simulating T2D in vitro, including hyperglycemia, hyperlipidemia, and...
4.
Tchoe Y, Wu T, U H, Roth D, Kim D, Lee J, et al.
bioRxiv
. 2023 Jul;
PMID: 37503216
Brain surgeries are among the most delicate clinical procedures and must be performed with the most technologically robust and advanced tools. When such surgical procedures are performed in functionally critical...
5.
Song Y, Leem J, Dhanani M, McKirnan M, Ichikawa Y, Braza J, et al.
PLoS One
. 2023 Feb;
18(2):e0281550.
PMID: 36780477
Role of blood-based factors in development and progression of heart failure (HF) is poorly characterized. Blood contains factors released during pathophysiological states that may impact cellular function and provide mechanistic...
6.
Wang S, Ichinomiya T, Savchenko P, Wang D, Sawada A, Li X, et al.
Theranostics
. 2022 Aug;
12(12):5389-5403.
PMID: 35910808
Elevating neuroprotective proteins using adeno-associated virus (AAV)-mediated gene delivery shows great promise in combating devastating neurodegenerative diseases. Amyotrophic lateral sclerosis (ALS) is one such disease resulting from loss of upper...
7.
Zhou Y, Patel H, Roth D
Anesth Analg
. 2021 Jul;
133(5):1162-1179.
PMID: 34304233
Extracellular vesicles (EVs) play critical roles in many health and disease states, including ischemia, inflammation, and pain, which are major concerns in the perioperative period and in critically ill patients....
8.
Wang S, Leem J, Podvin S, Hook V, Kleschevnikov N, Savchenko P, et al.
Mol Ther Methods Clin Dev
. 2021 May;
21:434-450.
PMID: 33981778
Alzheimer's disease (AD) is the most common form of neurodegeneration and cognitive dysfunction in the elderly. Identifying molecular signals that mitigate and reverse neurodegeneration in AD may be exploited therapeutically....
9.
Ying W, Tang K, Avolio E, Schilling J, Pasqua T, Liu M, et al.
Hypertension
. 2021 Apr;
77(5):1670-1682.
PMID: 33826401
[Figure: see text].
10.
Zemljic-Harpf A, Hoe L, Schilling J, Zuniga-Hertz J, Nguyen A, Vaishnav Y, et al.
FASEB J
. 2021 Feb;
35(3):e21407.
PMID: 33583084
The obesity epidemic has increased type II diabetes mellitus (T2DM) across developed countries. Cardiac T2DM risks include ischemic heart disease, heart failure with preserved ejection fraction, intolerance to ischemia-reperfusion (I-R)...