David M Mueller
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Explore the profile of David M Mueller including associated specialties, affiliations and a list of published articles.
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31
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1199
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Recent Articles
1.
Mueller D, Nathan D, Liu A, Mascarenhas J, Marcellino B
Leuk Res Rep
. 2024 Apr;
21:100458.
PMID: 38601955
Patients with inflammatory bowel disease (IBD) are exposed to chronic systemic inflammation and are at risk for secondary malignancies. Here we review the literature on the risk of myeloid neoplasms...
2.
Sharma S, Luo M, Patel H, Mueller D, Liao M
Nat Struct Mol Biol
. 2024 Feb;
31(4):657-666.
PMID: 38316880
Mitochondrial adenosine triphosphate (ATP) synthase uses the proton gradient across the inner mitochondrial membrane to synthesize ATP. Structural and single molecule studies conducted mostly at neutral or basic pH have...
3.
Chouhan S, Sawant M, Weimholt C, Luo J, Sprung R, Terrado M, et al.
Autophagy
. 2022 Jul;
19(3):1000-1025.
PMID: 35895804
The challenge of rapid macromolecular synthesis enforces the energy-hungry cancer cell mitochondria to switch their metabolic phenotypes, accomplished by activation of oncogenic tyrosine kinases. Precisely how kinase activity is directly...
4.
Su X, Dautant A, Rak M, Godard F, Ezkurdia N, Bouhier M, et al.
Hum Mol Genet
. 2021 Feb;
30(5):381-392.
PMID: 33600551
The human ATP synthase is an assembly of 29 subunits of 18 different types, of which only two (a and 8) are encoded in the mitochondrial genome. Subunit a, together...
5.
Moya-Mendez M, Mueller D, Pratt M, Bonner M, Elliott C, Hunanyan A, et al.
Epilepsy Behav
. 2021 Jan;
116:107732.
PMID: 33493807
Background: ATP1A2 mutations cause hemiplegic migraine with or without epilepsy or acute reversible encephalopathy. Typical onset is in adulthood or older childhood without subsequent severe long-term developmental impairments. Aim: We...
6.
Luo M, Zhou W, Patel H, Srivastava A, Symersky J, Bonar M, et al.
Commun Biol
. 2020 Aug;
3(1):452.
PMID: 32814813
Bedaquiline (BDQ, Sirturo) has been approved to treat multidrug resistant forms of Mycobacterium tuberculosis. Prior studies suggested that BDQ was a selective inhibitor of the ATP synthase from M. tuberculosis....
7.
Prange L, Pratt M, Herman K, Schiffmann R, Mueller D, McLean M, et al.
Neurol Genet
. 2020 Aug;
6(5):e466.
PMID: 32802951
Objective: To describe a phenotype caused by mutations, which manifests as dystonia, dysmorphism of the face, encephalopathy with developmental delay, brain MRI abnormalities always including cerebellar hypoplasia, no hemiplegia (Ø)...
8.
Kar T, Narsaria U, Basak S, Deb D, Castiglione F, Mueller D, et al.
Sci Rep
. 2020 Jul;
10(1):10895.
PMID: 32616763
In the past two decades, 7 coronaviruses have infected the human population, with two major outbreaks caused by SARS-CoV and MERS-CoV in the year 2002 and 2012, respectively. Currently, the...
9.
Christensen J, Craig E, Glista M, Mueller D, Li Y, Sees J, et al.
Mol Biol Cell
. 2019 Oct;
30(26):3123-3135.
PMID: 31664873
The regulated assembly of multiple filamentous actin (F-actin) networks from an actin monomer pool is important for a variety of cellular processes. is a unicellular green alga expressing a conventional...
10.
Craig E, Mueller D, Bigge B, Schaffer M, Engel B, Avasthi P
Mol Biol Cell
. 2019 Sep;
30(22):2827-2837.
PMID: 31532705
The green alga is a leading model system to study photosynthesis, cilia, and the generation of biological products. The cytoskeleton plays important roles in all of these cellular processes, but...