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David M Lynn

Explore the profile of David M Lynn including associated specialties, affiliations and a list of published articles. Areas
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Articles 142
Citations 2053
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Recent Articles
1.
Chang D, Richardson J, Lee M, Lynn D, Palecek S, Van Lehn R
Chem Sci . 2025 Mar; PMID: 40028619
Antimicrobial peptides (AMPs) are promising compounds for the treatment and prevention of multidrug-resistant infections because of their ability to directly disrupt microbial membranes, a mechanism that is less likely to...
2.
Chen L, Quinn L, York J, Polaske T, Nelson A, Appadoo V, et al.
ACS Omega . 2025 Mar; 10(7):7295-7305. PMID: 40028086
The ability to prevent bacterial adhesion on surfaces and to facilitate the removal of bacteria once they have already contaminated or colonized a surface is important in a broad range...
3.
Pineres-Quinones O, Onate-Socarras M, Wang F, Lynn D, Acevedo-Velez C
Langmuir . 2024 Feb; PMID: 38320298
We report emulsions of thermotropic liquid crystals (LCs) in water that are stabilized using amphiphilic gold nanoparticles (AuNPs) and retain their ability to respond to aqueous analytes for extended periods...
4.
Chang H, Chang D, Stamoulis A, Huber G, Lynn D, Palecek S, et al.
Green Chem . 2024 Jan; 25(14):5416-5427. PMID: 38223356
A biomass-derived difuran compound, denoted as HAH (HMF-Acetone-HMF), synthesized by aldol-condensation of 5-hydroxyfurfural (HMF) and acetone, can be partially hydrogenated to provide an electron-rich difuran compound (PHAH) for Diels-Alder reactions...
5.
Chang D, Lee M, Wang N, Lynn D, Palecek S
ACS Infect Dis . 2023 Nov; 9(12):2632-2651. PMID: 38014670
Antimicrobial peptides (AMPs) are promising candidates to combat pathogens that are resistant to conventional antimicrobial drugs because they operate through mechanisms that involve membrane disruption. However, the use of AMPs...
6.
Wang F, Qin S, Acevedo-Velez C, Van Lehn R, Zavala V, Lynn D
ACS Appl Mater Interfaces . 2023 Oct; 15(43):50532-50545. PMID: 37856671
Surfactants and other amphiphilic molecules are used extensively in household products, industrial processes, and biological applications and are also common environmental contaminants; as such, methods that can detect, sense, or...
7.
Gahan C, Van Lehn R, Blackwell H, Lynn D
Langmuir . 2022 Dec; 39(1):295-307. PMID: 36534123
We report the influence of membrane composition on the multiscale remodeling of multicomponent lipid bilayers initiated by contact with the amphiphilic bacterial quorum sensing signal -(3-oxo)-dodecanoyl-l-homoserine lactone (3-oxo-C12-AHL) and its...
8.
Appadoo V, Carter M, Jennings J, Guo X, Liu B, Hacker T, et al.
ACS Biomater Sci Eng . 2022 Sep; 8(10):4390-4401. PMID: 36130280
We report the design and characterization of thin polymer-based coatings that promote the contact transfer of DNA to soft surfaces under mild and physiologically relevant conditions. Past studies reveal polymer...
9.
Yu Y, Appadoo V, Ren J, Hacker T, Liu B, Lynn D
ACS Biomater Sci Eng . 2022 Sep; 8(10):4377-4389. PMID: 36121432
We report the design and characterization of pH-responsive polymer coatings that enable catheter balloon-mediated transfer of DNA to arterial tissue in short, clinically relevant inflation times. Our approach exploits the...
10.
Speetjens 2nd F, Carter M, Kim M, Gopalan P, Mahanthappa M, Lynn D
ACS Macro Lett . 2022 May; 3(11):1178-1182. PMID: 35610820
We report an approach to the post-fabrication placement of chemical functionality on microphase-separated thin films of a reactive block copolymer. Our approach makes use of an azlactone-containing block copolymer that...