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David Lodge

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Articles 47
Citations 995
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Recent Articles
11.
Ingram R, Kang H, Lightman S, Jane D, Bortolotto Z, Collingridge G, et al.
Neuropharmacology . 2018 Jun; 142:30-40. PMID: 29885421
Ketamine, a channel blocking NMDA receptor antagonist, is used off-label for its psychedelic effects, which may arise from a combination of several inter-related actions. Firstly, reductions of the contribution of...
12.
Mastroiacovo F, Moyanova S, Cannella M, Gaglione A, Verhaeghe R, Bozza G, et al.
Mol Brain . 2017 Aug; 10(1):39. PMID: 28821279
We have recently shown that pharmacological blockade of mGlu2 metabotropic glutamate receptors protects vulnerable neurons in the 4-vessel occlusion model of transient global ischemia, whereas receptor activation amplifies neuronal death....
13.
Collingridge G, Lee Y, Bortolotto Z, Kang H, Lodge D
Biol Psychiatry . 2016 Nov; 81(8):e65-e67. PMID: 27817845
No abstract available.
14.
Collingridge G, Lodge D, Mayer M, Turrigiano G, Frenguelli B
Neuropharmacology . 2016 Sep; 112(Pt A):1-3. PMID: 27659748
No abstract available.
15.
Kang H, Park P, Bortolotto Z, Brandt S, Colestock T, Wallach J, et al.
Neuropharmacology . 2016 Aug; 112(Pt A):144-149. PMID: 27520396
To avoid legislation based on chemical structure, research chemicals, frequently used for recreational purposes, are continually being synthesized. N-Ethyl-1,2-diphenylethanamine (ephenidine) is a diarylethylamine that has recently become popular with recreational...
16.
Wallach J, Kang H, Colestock T, Morris H, Bortolotto Z, Collingridge G, et al.
PLoS One . 2016 Jun; 11(6):e0157021. PMID: 27314670
1,2-Diarylethylamines including lanicemine, lefetamine, and remacemide have clinical relevance in a range of therapeutic areas including pain management, epilepsy, neurodegenerative disease and depression. More recently 1,2-diarylethylamines have been sold as...
17.
Wood C, Nicolas C, Choi S, Roman E, Nylander I, Fernandez-Teruel A, et al.
Neuropharmacology . 2016 Mar; 115:128-138. PMID: 26987983
Modulation of metabotropic glutamate 2 (mGlu2) receptor function has huge potential for treating psychiatric and neurological diseases. Development of drugs acting on mGlu2 receptors depends on the development and use...
18.
Wallis J, Irvine M, Jane D, Lodge D, Collingridge G, Bortolotto Z
Hippocampus . 2015 Mar; 25(11):1407-17. PMID: 25821051
The roles of both kainate receptors (KARs) and metabotropic glutamate receptors (mGluRs) in mossy fiber long-term potentiation (MF-LTP) have been extensively studied in hippocampal brain slices, but the findings are...
19.
Mercier M, Lodge D
Neurochem Res . 2014 Aug; 39(10):1876-94. PMID: 25146900
Glutamate, the primary excitatory neurotransmitter in the central nervous system (CNS), exerts neuromodulatory actions via the activation of metabotropic glutamate (mGlu) receptors. There are eight known mGlu receptor subtypes (mGlu1-8),...
20.
Wallach J, Kavanagh P, McLaughlin G, Morris N, Power J, Elliott S, et al.
Drug Test Anal . 2014 Jul; 7(5):358-67. PMID: 25044512
Substances with the diphenylethylamine nucleus represent a recent addition to the product catalog of dissociative agents sold as 'research chemicals' on the Internet. Diphenidine, i.e. 1-(1,2-diphenylethyl)piperidine (1,2-DEP), is such an...