Graham L Collingridge
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Explore the profile of Graham L Collingridge including associated specialties, affiliations and a list of published articles.
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177
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7972
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Recent Articles
1.
Samsom J, Xu M, Avila A, Daskalakis A, Dai J, Gao X, et al.
Neuropsychopharmacology
. 2025 Feb;
PMID: 39987275
Protein interacting with C-kinase 1 (PICK1) is important for synaptic plasticity through directing transport of glutamate receptors and other proteins. PICK1 gene variants have been associated with schizophrenia. To examine...
2.
Park E, He C, Abbasi A, Tian M, Huang S, Wang L, et al.
Biomaterials
. 2025 Jan;
318:123142.
PMID: 39874644
The development of disease-modifying therapeutics for Alzheimer's disease remains challenging due to the complex pathology and the presence of the blood-brain barrier. Previously we have described the investigation of a...
3.
Borovac J, Rai J, Valencia M, Li H, Georgiou J, Collingridge G, et al.
Front Mol Neurosci
. 2024 Dec;
17:1479360.
PMID: 39660172
A major intracellular messenger implicated in synaptic plasticity and cognitive functions both in health and disease is cyclic GMP (cGMP). Utilizing a photoactivatable guanylyl cyclase (BlgC) actuator to increase cGMP...
4.
Collingridge G
Neuroscience
. 2024 Nov;
PMID: 39615648
Long-term potentiation (LTP) is a widely studied phenomenon since the underlying molecular mechanisms are widely believed to be critical for learning and memory and their dysregulation has been implicated in...
5.
Lesuis S, Park S, Hoorn A, Rashid A, Mocle A, Salter E, et al.
Cell
. 2024 Nov;
188(1):121-140.e20.
PMID: 39549697
Stress induces aversive memory overgeneralization, a hallmark of many psychiatric disorders. Memories are encoded by a sparse ensemble of neurons active during an event (an engram ensemble). We examined the...
6.
So R, Amano G, Stuart E, Ebrahim Amini A, Aguzzi A, Collingridge G, et al.
PLoS Pathog
. 2024 Sep;
20(9):e1012517.
PMID: 39264912
The cellular prion protein, PrPC, has been postulated to function as a receptor for α-synuclein, potentially facilitating cell-to-cell spreading and/or toxicity of α-synuclein aggregates in neurodegenerative disorders such as Parkinson's...
7.
Sullivan M, Tidball P, Yan Y, Intson K, Chen W, Xu Y, et al.
bioRxiv
. 2024 Sep;
PMID: 39229143
Objective: -related neurodevelopmental disorder ( -NDD) is characterized by clinically significant variation in the gene, which encodes the obligatory GluN1 subunit of N-methyl-D-aspartate receptors (NMDARs). The identified p.Tyr647Ser (Y647S) variant...
8.
Li X, Shi W, Zhao Z, Matsuura T, Lu J, Che J, et al.
Adv Sci (Weinh)
. 2024 Sep;
11(39):e2308444.
PMID: 39225597
The corticostriatal connection plays a crucial role in cognitive, emotional, and motor control. However, the specific roles and synaptic transmissions of corticostriatal connection are less studied, especially the corticostriatal transmission...
9.
Collingridge G, Jane D, Lodge D
Neuropharmacology
. 2024 Jun;
:110046.
PMID: 38897382
No abstract available.
10.
Ingram R, Volianskis R, Georgiou J, Jane D, Michael-Titus A, Collingridge G, et al.
Philos Trans R Soc Lond B Biol Sci
. 2024 Jun;
379(1906):20230239.
PMID: 38853568
-methyl-d-aspartate receptor (NMDAR)-dependent short- and long-term types of potentiation (STP and LTP, respectively) are frequently studied in the CA1 area of dorsal hippocampal slices (DHS). Far less is known about...