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David L Chinkes

Explore the profile of David L Chinkes including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Tuvdendorj D, Borsheim E, Sharp C, Zhang X, Barone C, Chinkes D, et al.
J Biol Chem . 2015 Jun; 290(29):17776-17783. PMID: 26032410
The effects of amino acid supply and insulin infusion on skin protein kinetics (fractional synthesis rate (FSR), fractional breakdown rate (FBR), and net balance (NB)) in pigs were investigated. Four-month-old...
2.
Tuvdendorj D, Zhang X, Chinkes D, Wang L, Wu Z, Rodriguez N, et al.
Metabolism . 2015 Feb; 64(5):580-7. PMID: 25682063
Objective: The liver plays a central role in regulating fat metabolism; however, it is not clear how the liver distributes the synthesized triglycerides (TGs) to storage and to the plasma....
3.
Tuvdendorj D, Chinkes D, Bahadorani J, Zhang X, Sheffield-Moore M, Killewich L, et al.
Metabolism . 2014 Oct; 63(12):1562-7. PMID: 25308445
Background: The use of stable isotope tracer techniques to measure muscle protein fractional synthesis rate (FSR) has been well established and widely used. The most common method that has been...
4.
Tuvdendorj D, Chinkes D, Herndon D, Zhang X, Wolfe R
Am J Physiol Endocrinol Metab . 2013 Jan; 304(6):E623-30. PMID: 23321475
The measurement of the fractional breakdown rate (FBR) of muscle proteins during physiological non-steady state of amino acids (AAs) presents some challenges. Therefore, the goal of the present experiment was...
5.
Tuvdendorj D, Chinkes D, Zhang X, Ferrando A, Elijah I, Mlcak R, et al.
Intensive Care Med . 2011 Jun; 37(8):1317-22. PMID: 21647721
Purpose: This study was performed to determine if there is an age-related specificity in the response of muscle protein metabolism to severe burn injury during acute hospitalization. This is a...
6.
Tuvdendorj D, Chinkes D, Zhang X, Suman O, Aarsland A, Ferrando A, et al.
Surgery . 2011 Feb; 149(5):645-53. PMID: 21333314
Background: We recently showed that mechanisms of protein turnover in skeletal muscle are unresponsive to amino acid (AA) infusion in severely burned pediatric patients at 6 months postinjury. In the...
7.
Zhang X, Chinkes D, Wu Z, Herndon D
Clin Nutr . 2011 Feb; 30(3):391-6. PMID: 21277659
Background & Aims: Arginine infusion has been demonstrated to increase wound protein deposition; however, the effects of its enteral supplementation on wound cell proliferation have not been studied. Methods: Skin...
8.
Tuvdendorj D, Chinkes D, Zhang X, Sheffield-Moore M, Herndon D
Ann Surg . 2011 Jan; 253(3):592-7. PMID: 21263308
Objective: To evaluate leg muscle, whole-body muscle, and whole-body nonmuscle protein response to anabolic signaling of amino acids in pediatric burn patients at 6 months after injury. Background: Burn injury...
9.
Tuvdendorj D, Zhang X, Chinkes D, Aarsland A, Kulp G, Jeschke M, et al.
Surgery . 2011 Jan; 149(4):512-8. PMID: 21236451
Background: In the treatment of burns, patients' own skin is the preferred material to cover burn wounds, resulting in the need to create a donor site wound. Enhancement of healing...
10.
McEntire S, Chinkes D, Herndon D, Suman O
J Burn Care Res . 2010 Jul; 31(4):624-30. PMID: 20616652
The authors have previously described thermoregulatory responses of severely burned children during submaximal exercise in a thermoneutral environment. However, the thermoregulatory response of burned children to exercise in the heat...